Mutation of a single residue promotes gating of vertebrate and invertebrate two-pore domain potassium channels

Mutations that modulate the activity of ion channels are essential tools to understand the biophysical determinants that control their gating. Here authors reveal the role played by a single residue in the second transmembrane domain of vertebrate and invertebrate two-pore domain potassium channels.

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Autores principales:	Ismail Ben Soussia, Sonia El Mouridi, Dawon Kang, Alice Leclercq-Blondel, Lamyaa Khoubza, Philippe Tardy, Nora Zariohi, Marie Gendrel, Florian Lesage, Eun-Jin Kim, Delphine Bichet, Olga Andrini, Thomas Boulin
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/89358a70ca0b4f15867e6e9b7f65b48a
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spelling	oai:doaj.org-article:89358a70ca0b4f15867e6e9b7f65b48a2021-12-02T15:35:32ZMutation of a single residue promotes gating of vertebrate and invertebrate two-pore domain potassium channels10.1038/s41467-019-08710-32041-1723https://doaj.org/article/89358a70ca0b4f15867e6e9b7f65b48a2019-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-08710-3https://doaj.org/toc/2041-1723Mutations that modulate the activity of ion channels are essential tools to understand the biophysical determinants that control their gating. Here authors reveal the role played by a single residue in the second transmembrane domain of vertebrate and invertebrate two-pore domain potassium channels.Ismail Ben SoussiaSonia El MouridiDawon KangAlice Leclercq-BlondelLamyaa KhoubzaPhilippe TardyNora ZariohiMarie GendrelFlorian LesageEun-Jin KimDelphine BichetOlga AndriniThomas BoulinNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Ismail Ben Soussia Sonia El Mouridi Dawon Kang Alice Leclercq-Blondel Lamyaa Khoubza Philippe Tardy Nora Zariohi Marie Gendrel Florian Lesage Eun-Jin Kim Delphine Bichet Olga Andrini Thomas Boulin Mutation of a single residue promotes gating of vertebrate and invertebrate two-pore domain potassium channels
description	Mutations that modulate the activity of ion channels are essential tools to understand the biophysical determinants that control their gating. Here authors reveal the role played by a single residue in the second transmembrane domain of vertebrate and invertebrate two-pore domain potassium channels.
format	article
author	Ismail Ben Soussia Sonia El Mouridi Dawon Kang Alice Leclercq-Blondel Lamyaa Khoubza Philippe Tardy Nora Zariohi Marie Gendrel Florian Lesage Eun-Jin Kim Delphine Bichet Olga Andrini Thomas Boulin
author_facet	Ismail Ben Soussia Sonia El Mouridi Dawon Kang Alice Leclercq-Blondel Lamyaa Khoubza Philippe Tardy Nora Zariohi Marie Gendrel Florian Lesage Eun-Jin Kim Delphine Bichet Olga Andrini Thomas Boulin
author_sort	Ismail Ben Soussia
title	Mutation of a single residue promotes gating of vertebrate and invertebrate two-pore domain potassium channels
title_short	Mutation of a single residue promotes gating of vertebrate and invertebrate two-pore domain potassium channels
title_full	Mutation of a single residue promotes gating of vertebrate and invertebrate two-pore domain potassium channels
title_fullStr	Mutation of a single residue promotes gating of vertebrate and invertebrate two-pore domain potassium channels
title_full_unstemmed	Mutation of a single residue promotes gating of vertebrate and invertebrate two-pore domain potassium channels
title_sort	mutation of a single residue promotes gating of vertebrate and invertebrate two-pore domain potassium channels
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/89358a70ca0b4f15867e6e9b7f65b48a
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Mutation of a single residue promotes gating of vertebrate and invertebrate two-pore domain potassium channels

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