First Identification and Genotyping of <i>Enterocytozoon bieneusi</i> and Prevalence of <i>Encephalitozoon intestinalis</i> in Patients with Acute Diarrhea in the Republic of Korea
<i>Encephalitozoon intestinalis</i> and <i>Enterocytozoon bieneusi</i> can cause diarrhea in humans, especially severe diarrhea in immunocompromised patients. However, there have been few studies on <i>Enc. intestinalis</i> and <i>Ent. bieneusi</i> in...
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Autores principales: | , , , , |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
MDPI AG
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/8939bfe3f04e40d689fb04aede85db07 |
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Sumario: | <i>Encephalitozoon intestinalis</i> and <i>Enterocytozoon bieneusi</i> can cause diarrhea in humans, especially severe diarrhea in immunocompromised patients. However, there have been few studies on <i>Enc. intestinalis</i> and <i>Ent. bieneusi</i> in patients with acute diarrhea in the Republic of Korea (ROK). In this study, fecal samples were collected from 1241 patients with acute diarrhea in 2020. Among these, 24 cases of <i>Enc. intestinalis</i> and one case of <i>Ent. bieneusi</i> were detected via PCR amplification of small subunit ribosomal RNA. Genotyping of the internal transcribed spacer region sequence revealed that the detected <i>Ent. bieneusi</i> genotype was in Group 1. This study provides the first evidence that <i>Ent. bieneusi</i> exists in humans in addition to animals in the ROK. To identify the causative agent, continuous monitoring of <i>Enc. intestinalis</i> and <i>Ent. bieneusi</i> is necessary for patients with acute diarrhea in the ROK. |
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