First Identification and Genotyping of Enterocytozoon bieneusi and Prevalence of Encephalitozoon intestinalis in Patients with Acute Diarrhea in the Republic of Korea

Encephalitozoon intestinalis and Enterocytozoon bieneusi can cause diarrhea in humans, especially severe diarrhea in immunocompromised patients. However, there have been few studies on Enc. intestinalis and Ent. bieneusi in...

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Autores principales:	Ji-Young Kwon, Ji-Ye Seo, Tae-Yun Kim, Hee-Il Lee, Jung-Won Ju
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	<i>Encephalitozoon intestinalis</i> <i>Enterocytozoon bieneusi</i> patient genotype phylogeny microsporidia Medicine R
Acceso en línea:	https://doaj.org/article/8939bfe3f04e40d689fb04aede85db07
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spelling	oai:doaj.org-article:8939bfe3f04e40d689fb04aede85db072021-11-25T18:38:10ZFirst Identification and Genotyping of <i>Enterocytozoon bieneusi</i> and Prevalence of <i>Encephalitozoon intestinalis</i> in Patients with Acute Diarrhea in the Republic of Korea10.3390/pathogens101114242076-0817https://doaj.org/article/8939bfe3f04e40d689fb04aede85db072021-11-01T00:00:00Zhttps://www.mdpi.com/2076-0817/10/11/1424https://doaj.org/toc/2076-0817<i>Encephalitozoon intestinalis</i> and <i>Enterocytozoon bieneusi</i> can cause diarrhea in humans, especially severe diarrhea in immunocompromised patients. However, there have been few studies on <i>Enc. intestinalis</i> and <i>Ent. bieneusi</i> in patients with acute diarrhea in the Republic of Korea (ROK). In this study, fecal samples were collected from 1241 patients with acute diarrhea in 2020. Among these, 24 cases of <i>Enc. intestinalis</i> and one case of <i>Ent. bieneusi</i> were detected via PCR amplification of small subunit ribosomal RNA. Genotyping of the internal transcribed spacer region sequence revealed that the detected <i>Ent. bieneusi</i> genotype was in Group 1. This study provides the first evidence that <i>Ent. bieneusi</i> exists in humans in addition to animals in the ROK. To identify the causative agent, continuous monitoring of <i>Enc. intestinalis</i> and <i>Ent. bieneusi</i> is necessary for patients with acute diarrhea in the ROK.Ji-Young KwonJi-Ye SeoTae-Yun KimHee-Il LeeJung-Won JuMDPI AGarticle<i>Encephalitozoon intestinalis</i><i>Enterocytozoon bieneusi</i>patientgenotypephylogenymicrosporidiaMedicineRENPathogens, Vol 10, Iss 1424, p 1424 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	<i>Encephalitozoon intestinalis</i> <i>Enterocytozoon bieneusi</i> patient genotype phylogeny microsporidia Medicine R
spellingShingle	<i>Encephalitozoon intestinalis</i> <i>Enterocytozoon bieneusi</i> patient genotype phylogeny microsporidia Medicine R Ji-Young Kwon Ji-Ye Seo Tae-Yun Kim Hee-Il Lee Jung-Won Ju First Identification and Genotyping of <i>Enterocytozoon bieneusi</i> and Prevalence of <i>Encephalitozoon intestinalis</i> in Patients with Acute Diarrhea in the Republic of Korea
description	<i>Encephalitozoon intestinalis</i> and <i>Enterocytozoon bieneusi</i> can cause diarrhea in humans, especially severe diarrhea in immunocompromised patients. However, there have been few studies on <i>Enc. intestinalis</i> and <i>Ent. bieneusi</i> in patients with acute diarrhea in the Republic of Korea (ROK). In this study, fecal samples were collected from 1241 patients with acute diarrhea in 2020. Among these, 24 cases of <i>Enc. intestinalis</i> and one case of <i>Ent. bieneusi</i> were detected via PCR amplification of small subunit ribosomal RNA. Genotyping of the internal transcribed spacer region sequence revealed that the detected <i>Ent. bieneusi</i> genotype was in Group 1. This study provides the first evidence that <i>Ent. bieneusi</i> exists in humans in addition to animals in the ROK. To identify the causative agent, continuous monitoring of <i>Enc. intestinalis</i> and <i>Ent. bieneusi</i> is necessary for patients with acute diarrhea in the ROK.
format	article
author	Ji-Young Kwon Ji-Ye Seo Tae-Yun Kim Hee-Il Lee Jung-Won Ju
author_facet	Ji-Young Kwon Ji-Ye Seo Tae-Yun Kim Hee-Il Lee Jung-Won Ju
author_sort	Ji-Young Kwon
title	First Identification and Genotyping of <i>Enterocytozoon bieneusi</i> and Prevalence of <i>Encephalitozoon intestinalis</i> in Patients with Acute Diarrhea in the Republic of Korea
title_short	First Identification and Genotyping of <i>Enterocytozoon bieneusi</i> and Prevalence of <i>Encephalitozoon intestinalis</i> in Patients with Acute Diarrhea in the Republic of Korea
title_full	First Identification and Genotyping of <i>Enterocytozoon bieneusi</i> and Prevalence of <i>Encephalitozoon intestinalis</i> in Patients with Acute Diarrhea in the Republic of Korea
title_fullStr	First Identification and Genotyping of <i>Enterocytozoon bieneusi</i> and Prevalence of <i>Encephalitozoon intestinalis</i> in Patients with Acute Diarrhea in the Republic of Korea
title_full_unstemmed	First Identification and Genotyping of <i>Enterocytozoon bieneusi</i> and Prevalence of <i>Encephalitozoon intestinalis</i> in Patients with Acute Diarrhea in the Republic of Korea
title_sort	first identification and genotyping of <i>enterocytozoon bieneusi</i> and prevalence of <i>encephalitozoon intestinalis</i> in patients with acute diarrhea in the republic of korea
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/8939bfe3f04e40d689fb04aede85db07
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First Identification and Genotyping of <i>Enterocytozoon bieneusi</i> and Prevalence of <i>Encephalitozoon intestinalis</i> in Patients with Acute Diarrhea in the Republic of Korea

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