Neurovascular EGFL7 regulates adult neurogenesis in the subventricular zone and thereby affects olfactory perception

Neurovascular EGFL7 regulates adult neurogenesis in the subventricular zone and thereby affects olfactory perception

The vascular stem cell niche regulates the proliferation and differentiation of neural stem cells (NSCs) in the adult subventricular zone. Here the authors identify EGFL7 as a neurovascular regulator of NSCsin vivo; EGFL7-knockout mice show reduced neurogenesis, and exhibit impaired olfactory percep...

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Autores principales: Frank Bicker, Verica Vasic, Guilherme Horta, Felipe Ortega, Hendrik Nolte, Atria Kavyanifar, Stefanie Keller, Nevenka Dudvarski Stankovic, Patrick N. Harter, Rui Benedito, Beat Lutz, Tobias Bäuerle, Jens Hartwig, Jan Baumgart, Marcus Krüger, Konstantin Radyushkin, Lavinia Alberi, Benedikt Berninger, Mirko H. H. Schmidt
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Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/893b1f84a39b4db9ad2ea276781e4fdb
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spelling oai:doaj.org-article:893b1f84a39b4db9ad2ea276781e4fdb2021-12-02T17:06:30ZNeurovascular EGFL7 regulates adult neurogenesis in the subventricular zone and thereby affects olfactory perception10.1038/ncomms159222041-1723https://doaj.org/article/893b1f84a39b4db9ad2ea276781e4fdb2017-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms15922https://doaj.org/toc/2041-1723The vascular stem cell niche regulates the proliferation and differentiation of neural stem cells (NSCs) in the adult subventricular zone. Here the authors identify EGFL7 as a neurovascular regulator of NSCsin vivo; EGFL7-knockout mice show reduced neurogenesis, and exhibit impaired olfactory perception and behaviour.Frank BickerVerica VasicGuilherme HortaFelipe OrtegaHendrik NolteAtria KavyanifarStefanie KellerNevenka Dudvarski StankovicPatrick N. HarterRui BeneditoBeat LutzTobias BäuerleJens HartwigJan BaumgartMarcus KrügerKonstantin RadyushkinLavinia AlberiBenedikt BerningerMirko H. H. SchmidtNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Frank Bicker
Verica Vasic
Guilherme Horta
Felipe Ortega
Hendrik Nolte
Atria Kavyanifar
Stefanie Keller
Nevenka Dudvarski Stankovic
Patrick N. Harter
Rui Benedito
Beat Lutz
Tobias Bäuerle
Jens Hartwig
Jan Baumgart
Marcus Krüger
Konstantin Radyushkin
Lavinia Alberi
Benedikt Berninger
Mirko H. H. Schmidt
Neurovascular EGFL7 regulates adult neurogenesis in the subventricular zone and thereby affects olfactory perception
description The vascular stem cell niche regulates the proliferation and differentiation of neural stem cells (NSCs) in the adult subventricular zone. Here the authors identify EGFL7 as a neurovascular regulator of NSCsin vivo; EGFL7-knockout mice show reduced neurogenesis, and exhibit impaired olfactory perception and behaviour.
format article
author Frank Bicker
Verica Vasic
Guilherme Horta
Felipe Ortega
Hendrik Nolte
Atria Kavyanifar
Stefanie Keller
Nevenka Dudvarski Stankovic
Patrick N. Harter
Rui Benedito
Beat Lutz
Tobias Bäuerle
Jens Hartwig
Jan Baumgart
Marcus Krüger
Konstantin Radyushkin
Lavinia Alberi
Benedikt Berninger
Mirko H. H. Schmidt
author_facet Frank Bicker
Verica Vasic
Guilherme Horta
Felipe Ortega
Hendrik Nolte
Atria Kavyanifar
Stefanie Keller
Nevenka Dudvarski Stankovic
Patrick N. Harter
Rui Benedito
Beat Lutz
Tobias Bäuerle
Jens Hartwig
Jan Baumgart
Marcus Krüger
Konstantin Radyushkin
Lavinia Alberi
Benedikt Berninger
Mirko H. H. Schmidt
author_sort Frank Bicker
title Neurovascular EGFL7 regulates adult neurogenesis in the subventricular zone and thereby affects olfactory perception
title_short Neurovascular EGFL7 regulates adult neurogenesis in the subventricular zone and thereby affects olfactory perception
title_full Neurovascular EGFL7 regulates adult neurogenesis in the subventricular zone and thereby affects olfactory perception
title_fullStr Neurovascular EGFL7 regulates adult neurogenesis in the subventricular zone and thereby affects olfactory perception
title_full_unstemmed Neurovascular EGFL7 regulates adult neurogenesis in the subventricular zone and thereby affects olfactory perception
title_sort neurovascular egfl7 regulates adult neurogenesis in the subventricular zone and thereby affects olfactory perception
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/893b1f84a39b4db9ad2ea276781e4fdb
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