Proton Image-guided Radiation Assignment for Therapeutic Escalation via Selection of locally advanced head and neck cancer patients [PIRATES]: A Phase I safety and feasibility trial of MRI-guided adaptive particle radiotherapy

Proton Image-guided Radiation Assignment for Therapeutic Escalation via Selection of locally advanced head and neck cancer patients [PIRATES]: A Phase I safety and feasibility trial of MRI-guided adaptive particle radiotherapy

Introduction: Radiation dose-escalation for head and neck cancer (HNC) patients aiming to improve cure rates is challenging due to the increased risk of unacceptable treatment-induced toxicities. With “Proton Image-guided Radiation Assignment for Therapeutic Escalation via Selection of locally advan...

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Bibliographic Details
Main Authors: Lisanne V. van Dijk, Steven J. Frank, Ying Yuan, Brandon Gunn, Amy C. Moreno, Abdallah S.R. Mohamed, Kathryn E. Preston, Yun Qing, Michael T. Spiotto, William H. Morrison, Anna Lee, Jack Phan, Adam S. Garden, David I. Rosenthal, Johannes A. Langendijk, Clifton D. Fuller
Format: article
Language:EN
Published: Elsevier 2022
Subjects:
Head and neck cancer
Radiation dose-escalation
Proton therapy
Image guided RT
Hyper-fractionation
Phase I trial
Medical physics. Medical radiology. Nuclear medicine
R895-920
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
Online Access:https://doaj.org/article/893d1d07fa6a4527a329dc4580851cb1
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https://doaj.org/article/893d1d07fa6a4527a329dc4580851cb1

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