DISTRIBUTION PATTERNS OF ALLELES AND GENOTYPES FOR HLA-G 3'UTR 14-bp ins/del IN MOTHERS OF CHILDREN WITH CONGENITAL HEART DEFECTS OR REPRODUCTIVE LOSSES AT EARLY GESTATION TERMS
HLA-G is the main molecule through which provides tolerance of maternal immune microenvironment to the semi-allogeneic embryo. Polymorphic variant of 14-bp ins/del in the HLA-G 3’UTR gene affects stability and expression of specific mRNA and, thereby, efficiency of immune rejection blockade of the s...
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Main Authors: | , , , , , |
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Format: | article |
Language: | RU |
Published: |
SPb RAACI
2017
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Subjects: | |
Online Access: | https://doaj.org/article/8943d0a645ec45f890e4605705aaed51 |
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