The complex of ferric-enterobactin with its transporter from Pseudomonas aeruginosa suggests a two-site model

Bacteria produce small iron-binding molecules called siderophores, which are recognised by outer-membrane transporters. Here, the authors show that a Pseudomonas transporter recognises the siderophore enterobactin using extracellular loops distant from the pore, and propose that there is a second bi...

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Autores principales:	Lucile Moynié, Stefan Milenkovic, Gaëtan L. A. Mislin, Véronique Gasser, Giuliano Malloci, Etienne Baco, Rory P. McCaughan, Malcolm G. P. Page, Isabelle J. Schalk, Matteo Ceccarelli, James H. Naismith
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/8945e5c4fd1a454a9808f2cc55ad41dc
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spelling	oai:doaj.org-article:8945e5c4fd1a454a9808f2cc55ad41dc2021-12-02T16:57:35ZThe complex of ferric-enterobactin with its transporter from Pseudomonas aeruginosa suggests a two-site model10.1038/s41467-019-11508-y2041-1723https://doaj.org/article/8945e5c4fd1a454a9808f2cc55ad41dc2019-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11508-yhttps://doaj.org/toc/2041-1723Bacteria produce small iron-binding molecules called siderophores, which are recognised by outer-membrane transporters. Here, the authors show that a Pseudomonas transporter recognises the siderophore enterobactin using extracellular loops distant from the pore, and propose that there is a second binding site deeper inside the structure.Lucile MoyniéStefan MilenkovicGaëtan L. A. MislinVéronique GasserGiuliano MallociEtienne BacoRory P. McCaughanMalcolm G. P. PageIsabelle J. SchalkMatteo CeccarelliJames H. NaismithNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Lucile Moynié Stefan Milenkovic Gaëtan L. A. Mislin Véronique Gasser Giuliano Malloci Etienne Baco Rory P. McCaughan Malcolm G. P. Page Isabelle J. Schalk Matteo Ceccarelli James H. Naismith The complex of ferric-enterobactin with its transporter from Pseudomonas aeruginosa suggests a two-site model
description	Bacteria produce small iron-binding molecules called siderophores, which are recognised by outer-membrane transporters. Here, the authors show that a Pseudomonas transporter recognises the siderophore enterobactin using extracellular loops distant from the pore, and propose that there is a second binding site deeper inside the structure.
format	article
author	Lucile Moynié Stefan Milenkovic Gaëtan L. A. Mislin Véronique Gasser Giuliano Malloci Etienne Baco Rory P. McCaughan Malcolm G. P. Page Isabelle J. Schalk Matteo Ceccarelli James H. Naismith
author_facet	Lucile Moynié Stefan Milenkovic Gaëtan L. A. Mislin Véronique Gasser Giuliano Malloci Etienne Baco Rory P. McCaughan Malcolm G. P. Page Isabelle J. Schalk Matteo Ceccarelli James H. Naismith
author_sort	Lucile Moynié
title	The complex of ferric-enterobactin with its transporter from Pseudomonas aeruginosa suggests a two-site model
title_short	The complex of ferric-enterobactin with its transporter from Pseudomonas aeruginosa suggests a two-site model
title_full	The complex of ferric-enterobactin with its transporter from Pseudomonas aeruginosa suggests a two-site model
title_fullStr	The complex of ferric-enterobactin with its transporter from Pseudomonas aeruginosa suggests a two-site model
title_full_unstemmed	The complex of ferric-enterobactin with its transporter from Pseudomonas aeruginosa suggests a two-site model
title_sort	complex of ferric-enterobactin with its transporter from pseudomonas aeruginosa suggests a two-site model
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/8945e5c4fd1a454a9808f2cc55ad41dc
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The complex of ferric-enterobactin with its transporter from Pseudomonas aeruginosa suggests a two-site model

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