Whole exome sequencing for the identification of CYP3A7 variants associated with tacrolimus concentrations in kidney transplant patients

Abstract The purpose of this study was to identify genotypes associated with dose-adjusted tacrolimus trough concentrations (C0/D) in kidney transplant recipients using whole-exome sequencing (WES). This study included 147 patients administered tacrolimus, including seventy-five patients in the disc...

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Autores principales: Minji Sohn, Myeong Gyu Kim, Nayoung Han, In-Wha Kim, Jungsoo Gim, Sang-Il Min, Eun Young Song, Yon Su Kim, Hun Soon Jung, Young Kee Shin, Jongwon Ha, Jung Mi Oh
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/8957da4f57f14db5b4a9a5980b9a6754
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