Whole exome sequencing for the identification of CYP3A7 variants associated with tacrolimus concentrations in kidney transplant patients

Whole exome sequencing for the identification of CYP3A7 variants associated with tacrolimus concentrations in kidney transplant patients

Abstract The purpose of this study was to identify genotypes associated with dose-adjusted tacrolimus trough concentrations (C0/D) in kidney transplant recipients using whole-exome sequencing (WES). This study included 147 patients administered tacrolimus, including seventy-five patients in the disc...

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Autores principales: Minji Sohn, Myeong Gyu Kim, Nayoung Han, In-Wha Kim, Jungsoo Gim, Sang-Il Min, Eun Young Song, Yon Su Kim, Hun Soon Jung, Young Kee Shin, Jongwon Ha, Jung Mi Oh
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/8957da4f57f14db5b4a9a5980b9a6754
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