VPO1 mediates ApoE oxidation and impairs the clearance of plasma lipids.

<h4>Objective</h4>ApoE is an abundant component of chylomicron, VLDL, IDL, and HDL. It binds to multiple types of lipids and is implicated in cholesterol and triglyceride homeostasis. Oxidation of ApoE plays a crucial role in the genesis of atherosclerosis. It is proposed that heme-conta...

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Autores principales: Youfeng Yang, Zehong Cao, Ling Tian, W Timothy Garvey, Guangjie Cheng
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/895833b63d5543c3906fef42e59d62df
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