Synergistic activation of mutant TERT promoter by Sp1 and GABPA in BRAFV600E-driven human cancers
Abstract The activating TERT promoter mutations and BRAF V600E mutation are well-established oncogenic alterations in human cancers. Coexistence of BRAF V600E and TERT promoter mutations is frequently found in multiple cancer types, and is strongly associated with poor patient prognosis. Although th...
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| Autores principales: | , , , , , , , , , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2021
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/8960613512794ea8858c81b1f6b48e74 |
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