The Incidence of Bacteremia and Risk Factors of Post-Radiofrequency Ablation Fever for Patients with Hepato-Cellular Carcinoma

Post-radiofrequency ablation (RFA) fever is a self-limited complication of RFA. The correlation between post-RFA fever and bacteremia and the risk factors associated with post-RFA fever have not been evaluated. Patients with newly diagnosed or recurrent hepatocellular carcinoma who underwent ultraso...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Po-Yueh Chen, Tsung-Jung Tsai, Hsin-Yi Yang, Chu-Kuang Chou, Li-Jen Chang, Tsung-Hsien Chen, Ming-Tse Hsu, Chien-Chung Fang, Chang-Chao Su, Yu-Ling Lin, Yu-Min Feng, Chi-Yi Chen
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	radiofrequency ablation hepatocellular carcinoma fever Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Acceso en línea:	https://doaj.org/article/8962d931ccad440d9b172cfaecc14191
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:8962d931ccad440d9b172cfaecc14191
record_format	dspace
spelling	oai:doaj.org-article:8962d931ccad440d9b172cfaecc141912021-11-11T15:27:45ZThe Incidence of Bacteremia and Risk Factors of Post-Radiofrequency Ablation Fever for Patients with Hepato-Cellular Carcinoma10.3390/cancers132153032072-6694https://doaj.org/article/8962d931ccad440d9b172cfaecc141912021-10-01T00:00:00Zhttps://www.mdpi.com/2072-6694/13/21/5303https://doaj.org/toc/2072-6694Post-radiofrequency ablation (RFA) fever is a self-limited complication of RFA. The correlation between post-RFA fever and bacteremia and the risk factors associated with post-RFA fever have not been evaluated. Patients with newly diagnosed or recurrent hepatocellular carcinoma who underwent ultrasonography-guided RFA between April 2014 and February 2019 were retrospectively enrolled. Post-RFA fever was defined as any episode of body temperature >38.0 °C after RFA during hospitalization. A total of 272 patients were enrolled, and there were 452 applications of RFA. The frequency of post-RFA fever was 18.4% (83/452), and 65.1% (54/83) of post-RFA fevers occurred on the first day after ablation. Patients with post-RFA fever had a longer hospital stay than those without (9.06 days vs. 5.50 days, <i>p</i> < 0.001). Only four (4.8%) patients with post-RFA fever had bacteremia. The independent factors associated with post-RFA fever were younger age (adjusted odds ratio (OR) = 0.96, 95% CI, 0.94–0.99, <i>p</i> = 0.019), low serum albumin level (adjusted OR = 0.49, 95% CI, 0.25–0.95, <i>p</i> = 0.036), general anesthesia (adjusted OR = 2.06, 95% CI, 1.15–3.69, <i>p</i> = 0.015), tumor size (adjusted OR = 1.52, 95% CI, 1.04–2.02, <i>p</i> = 0.032), and tumor number (adjusted OR = 1.71, 95% CI, 1.20–2.45, <i>p</i> = 0.003).Po-Yueh ChenTsung-Jung TsaiHsin-Yi YangChu-Kuang ChouLi-Jen ChangTsung-Hsien ChenMing-Tse HsuChien-Chung FangChang-Chao SuYu-Ling LinYu-Min FengChi-Yi ChenMDPI AGarticleradiofrequency ablationhepatocellular carcinomafeverNeoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282ENCancers, Vol 13, Iss 5303, p 5303 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	radiofrequency ablation hepatocellular carcinoma fever Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
spellingShingle	radiofrequency ablation hepatocellular carcinoma fever Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 Po-Yueh Chen Tsung-Jung Tsai Hsin-Yi Yang Chu-Kuang Chou Li-Jen Chang Tsung-Hsien Chen Ming-Tse Hsu Chien-Chung Fang Chang-Chao Su Yu-Ling Lin Yu-Min Feng Chi-Yi Chen The Incidence of Bacteremia and Risk Factors of Post-Radiofrequency Ablation Fever for Patients with Hepato-Cellular Carcinoma
description	Post-radiofrequency ablation (RFA) fever is a self-limited complication of RFA. The correlation between post-RFA fever and bacteremia and the risk factors associated with post-RFA fever have not been evaluated. Patients with newly diagnosed or recurrent hepatocellular carcinoma who underwent ultrasonography-guided RFA between April 2014 and February 2019 were retrospectively enrolled. Post-RFA fever was defined as any episode of body temperature >38.0 °C after RFA during hospitalization. A total of 272 patients were enrolled, and there were 452 applications of RFA. The frequency of post-RFA fever was 18.4% (83/452), and 65.1% (54/83) of post-RFA fevers occurred on the first day after ablation. Patients with post-RFA fever had a longer hospital stay than those without (9.06 days vs. 5.50 days, <i>p</i> < 0.001). Only four (4.8%) patients with post-RFA fever had bacteremia. The independent factors associated with post-RFA fever were younger age (adjusted odds ratio (OR) = 0.96, 95% CI, 0.94–0.99, <i>p</i> = 0.019), low serum albumin level (adjusted OR = 0.49, 95% CI, 0.25–0.95, <i>p</i> = 0.036), general anesthesia (adjusted OR = 2.06, 95% CI, 1.15–3.69, <i>p</i> = 0.015), tumor size (adjusted OR = 1.52, 95% CI, 1.04–2.02, <i>p</i> = 0.032), and tumor number (adjusted OR = 1.71, 95% CI, 1.20–2.45, <i>p</i> = 0.003).
format	article
author	Po-Yueh Chen Tsung-Jung Tsai Hsin-Yi Yang Chu-Kuang Chou Li-Jen Chang Tsung-Hsien Chen Ming-Tse Hsu Chien-Chung Fang Chang-Chao Su Yu-Ling Lin Yu-Min Feng Chi-Yi Chen
author_facet	Po-Yueh Chen Tsung-Jung Tsai Hsin-Yi Yang Chu-Kuang Chou Li-Jen Chang Tsung-Hsien Chen Ming-Tse Hsu Chien-Chung Fang Chang-Chao Su Yu-Ling Lin Yu-Min Feng Chi-Yi Chen
author_sort	Po-Yueh Chen
title	The Incidence of Bacteremia and Risk Factors of Post-Radiofrequency Ablation Fever for Patients with Hepato-Cellular Carcinoma
title_short	The Incidence of Bacteremia and Risk Factors of Post-Radiofrequency Ablation Fever for Patients with Hepato-Cellular Carcinoma
title_full	The Incidence of Bacteremia and Risk Factors of Post-Radiofrequency Ablation Fever for Patients with Hepato-Cellular Carcinoma
title_fullStr	The Incidence of Bacteremia and Risk Factors of Post-Radiofrequency Ablation Fever for Patients with Hepato-Cellular Carcinoma
title_full_unstemmed	The Incidence of Bacteremia and Risk Factors of Post-Radiofrequency Ablation Fever for Patients with Hepato-Cellular Carcinoma
title_sort	incidence of bacteremia and risk factors of post-radiofrequency ablation fever for patients with hepato-cellular carcinoma
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/8962d931ccad440d9b172cfaecc14191
work_keys_str_mv	AT poyuehchen theincidenceofbacteremiaandriskfactorsofpostradiofrequencyablationfeverforpatientswithhepatocellularcarcinoma AT tsungjungtsai theincidenceofbacteremiaandriskfactorsofpostradiofrequencyablationfeverforpatientswithhepatocellularcarcinoma AT hsinyiyang theincidenceofbacteremiaandriskfactorsofpostradiofrequencyablationfeverforpatientswithhepatocellularcarcinoma AT chukuangchou theincidenceofbacteremiaandriskfactorsofpostradiofrequencyablationfeverforpatientswithhepatocellularcarcinoma AT lijenchang theincidenceofbacteremiaandriskfactorsofpostradiofrequencyablationfeverforpatientswithhepatocellularcarcinoma AT tsunghsienchen theincidenceofbacteremiaandriskfactorsofpostradiofrequencyablationfeverforpatientswithhepatocellularcarcinoma AT mingtsehsu theincidenceofbacteremiaandriskfactorsofpostradiofrequencyablationfeverforpatientswithhepatocellularcarcinoma AT chienchungfang theincidenceofbacteremiaandriskfactorsofpostradiofrequencyablationfeverforpatientswithhepatocellularcarcinoma AT changchaosu theincidenceofbacteremiaandriskfactorsofpostradiofrequencyablationfeverforpatientswithhepatocellularcarcinoma AT yulinglin theincidenceofbacteremiaandriskfactorsofpostradiofrequencyablationfeverforpatientswithhepatocellularcarcinoma AT yuminfeng theincidenceofbacteremiaandriskfactorsofpostradiofrequencyablationfeverforpatientswithhepatocellularcarcinoma AT chiyichen theincidenceofbacteremiaandriskfactorsofpostradiofrequencyablationfeverforpatientswithhepatocellularcarcinoma AT poyuehchen incidenceofbacteremiaandriskfactorsofpostradiofrequencyablationfeverforpatientswithhepatocellularcarcinoma AT tsungjungtsai incidenceofbacteremiaandriskfactorsofpostradiofrequencyablationfeverforpatientswithhepatocellularcarcinoma AT hsinyiyang incidenceofbacteremiaandriskfactorsofpostradiofrequencyablationfeverforpatientswithhepatocellularcarcinoma AT chukuangchou incidenceofbacteremiaandriskfactorsofpostradiofrequencyablationfeverforpatientswithhepatocellularcarcinoma AT lijenchang incidenceofbacteremiaandriskfactorsofpostradiofrequencyablationfeverforpatientswithhepatocellularcarcinoma AT tsunghsienchen incidenceofbacteremiaandriskfactorsofpostradiofrequencyablationfeverforpatientswithhepatocellularcarcinoma AT mingtsehsu incidenceofbacteremiaandriskfactorsofpostradiofrequencyablationfeverforpatientswithhepatocellularcarcinoma AT chienchungfang incidenceofbacteremiaandriskfactorsofpostradiofrequencyablationfeverforpatientswithhepatocellularcarcinoma AT changchaosu incidenceofbacteremiaandriskfactorsofpostradiofrequencyablationfeverforpatientswithhepatocellularcarcinoma AT yulinglin incidenceofbacteremiaandriskfactorsofpostradiofrequencyablationfeverforpatientswithhepatocellularcarcinoma AT yuminfeng incidenceofbacteremiaandriskfactorsofpostradiofrequencyablationfeverforpatientswithhepatocellularcarcinoma AT chiyichen incidenceofbacteremiaandriskfactorsofpostradiofrequencyablationfeverforpatientswithhepatocellularcarcinoma
_version_	1718435251128107008

The Incidence of Bacteremia and Risk Factors of Post-Radiofrequency Ablation Fever for Patients with Hepato-Cellular Carcinoma

Ejemplares similares