Cognitive impairment in patients with atrial fibrillation without stroke

Background: Vascular dementia is the second leading cause of dementia worldwide; however, the causation is multifactorial and may be preventable. There is increasing evidence that atrial fibrillation (AF) is independently correlated with cognitive decline. Assessing cognition in an outpatient settin...

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Autores principales:	Vineeth Jaison, Sarah Sharma, Himani Khatter, Rajneesh Calton, Jeyaraj Durai Pandian, Mahesh Pundlik Kate
Formato:	article
Lenguaje:	EN
Publicado:	Wolters Kluwer Medknow Publications 2021
Materias:	atrial fibrillation cognition dementia gait velocity Medicine R Nursing RT1-120
Acceso en línea:	https://doaj.org/article/89644b2f741d4925aeeb4fb31fc4be2a
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spelling	oai:doaj.org-article:89644b2f741d4925aeeb4fb31fc4be2a2021-11-12T10:09:47ZCognitive impairment in patients with atrial fibrillation without stroke2348-33342348-506X10.4103/cjhr.cjhr_81_19https://doaj.org/article/89644b2f741d4925aeeb4fb31fc4be2a2021-01-01T00:00:00Zhttp://www.cjhr.org/article.asp?issn=2348-3334;year=2021;volume=8;issue=2;spage=84;epage=88;aulast=Jaisonhttps://doaj.org/toc/2348-3334https://doaj.org/toc/2348-506XBackground: Vascular dementia is the second leading cause of dementia worldwide; however, the causation is multifactorial and may be preventable. There is increasing evidence that atrial fibrillation (AF) is independently correlated with cognitive decline. Assessing cognition in an outpatient setting is challenging. Gait speed may be able to transcend language in assessing cognition. We aim to assess cognitive impairment in patients with AF without known history of stroke with gait speed. Methods: This was a prospective, observational study of patients attending cardiology outpatient department. Patients were screened for a history of valvular or nonvalvular AF. Controls were patients without AF. Patients underwent structured interview, Montreal cognitive assessment (MoCA), and gait velocity assessment. Gait velocity and MoCA scores were compared in control and cases using Student's t-test. Results: A total of 189 patients were consented; 88 cases with AF and 101 controls. Mean ± standard deviation age was 60 ± 12 years. The median (interquartile range) gait velocity in patients with AF and nonAF was similar (0.80 [0.65–0.93] m/s vs. 0.80 [0.65–0.93] m/s, P = 0.708). The mean MoCA scores in patients with AF and without AF were also similar (17.38 ± 5.66 vs. 18.36 ± 5.30, P = 0.229). A cutoff value of <0.80 m/s had sensitivity of 66% and specificity of 61.4% to diagnose dementia. Conclusion: There is a high occurrence of cognitive deficits in patients with and without AF visiting a cardiology outpatient clinic. Future studies are needed to target this group of the patient to reduce the burden of vascular dementia.Vineeth JaisonSarah SharmaHimani KhatterRajneesh CaltonJeyaraj Durai PandianMahesh Pundlik KateWolters Kluwer Medknow Publicationsarticle atrial fibrillationcognitiondementiagait velocity MedicineRNursingRT1-120ENCHRISMED Journal of Health and Research, Vol 8, Iss 2, Pp 84-88 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	atrial fibrillation cognition dementia gait velocity Medicine R Nursing RT1-120
spellingShingle	atrial fibrillation cognition dementia gait velocity Medicine R Nursing RT1-120 Vineeth Jaison Sarah Sharma Himani Khatter Rajneesh Calton Jeyaraj Durai Pandian Mahesh Pundlik Kate Cognitive impairment in patients with atrial fibrillation without stroke
description	Background: Vascular dementia is the second leading cause of dementia worldwide; however, the causation is multifactorial and may be preventable. There is increasing evidence that atrial fibrillation (AF) is independently correlated with cognitive decline. Assessing cognition in an outpatient setting is challenging. Gait speed may be able to transcend language in assessing cognition. We aim to assess cognitive impairment in patients with AF without known history of stroke with gait speed. Methods: This was a prospective, observational study of patients attending cardiology outpatient department. Patients were screened for a history of valvular or nonvalvular AF. Controls were patients without AF. Patients underwent structured interview, Montreal cognitive assessment (MoCA), and gait velocity assessment. Gait velocity and MoCA scores were compared in control and cases using Student's t-test. Results: A total of 189 patients were consented; 88 cases with AF and 101 controls. Mean ± standard deviation age was 60 ± 12 years. The median (interquartile range) gait velocity in patients with AF and nonAF was similar (0.80 [0.65–0.93] m/s vs. 0.80 [0.65–0.93] m/s, P = 0.708). The mean MoCA scores in patients with AF and without AF were also similar (17.38 ± 5.66 vs. 18.36 ± 5.30, P = 0.229). A cutoff value of <0.80 m/s had sensitivity of 66% and specificity of 61.4% to diagnose dementia. Conclusion: There is a high occurrence of cognitive deficits in patients with and without AF visiting a cardiology outpatient clinic. Future studies are needed to target this group of the patient to reduce the burden of vascular dementia.
format	article
author	Vineeth Jaison Sarah Sharma Himani Khatter Rajneesh Calton Jeyaraj Durai Pandian Mahesh Pundlik Kate
author_facet	Vineeth Jaison Sarah Sharma Himani Khatter Rajneesh Calton Jeyaraj Durai Pandian Mahesh Pundlik Kate
author_sort	Vineeth Jaison
title	Cognitive impairment in patients with atrial fibrillation without stroke
title_short	Cognitive impairment in patients with atrial fibrillation without stroke
title_full	Cognitive impairment in patients with atrial fibrillation without stroke
title_fullStr	Cognitive impairment in patients with atrial fibrillation without stroke
title_full_unstemmed	Cognitive impairment in patients with atrial fibrillation without stroke
title_sort	cognitive impairment in patients with atrial fibrillation without stroke
publisher	Wolters Kluwer Medknow Publications
publishDate	2021
url	https://doaj.org/article/89644b2f741d4925aeeb4fb31fc4be2a
work_keys_str_mv	AT vineethjaison cognitiveimpairmentinpatientswithatrialfibrillationwithoutstroke AT sarahsharma cognitiveimpairmentinpatientswithatrialfibrillationwithoutstroke AT himanikhatter cognitiveimpairmentinpatientswithatrialfibrillationwithoutstroke AT rajneeshcalton cognitiveimpairmentinpatientswithatrialfibrillationwithoutstroke AT jeyarajduraipandian cognitiveimpairmentinpatientswithatrialfibrillationwithoutstroke AT maheshpundlikkate cognitiveimpairmentinpatientswithatrialfibrillationwithoutstroke
_version_	1718431061673771008

Cognitive impairment in patients with atrial fibrillation without stroke

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