Hypoglossal nerve stimulation for obstructive sleep apnea: A review of the literature
Objective: To review the indications and clinical evidence supporting hypoglossal nerve stimulation (HNS) therapy for the treatment of moderate-to-severe obstructive sleep apnea (OSA). Methods: Peer reviewed literature on hypoglossal nerve stimulation therapy for obstructive sleep apnea from 2001 to...
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| Autores principales: | , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
KeAi Communications Co., Ltd.
2016
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/897a3f4ffc3641efbeafb00ee87f3f27 |
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| Sumario: | Objective: To review the indications and clinical evidence supporting hypoglossal nerve stimulation (HNS) therapy for the treatment of moderate-to-severe obstructive sleep apnea (OSA). Methods: Peer reviewed literature on hypoglossal nerve stimulation therapy for obstructive sleep apnea from 2001 to 2016. Results: The only currently FDA-approved HNS device for the treatment of moderate-to-severe OSA is produced by Inspire Medical Systems, which recently published its 36-month outcomes data from its Stimulation Therapy for Apnea Reduction (STAR) trial. HNS therapy is currently indicated for moderate-to-severe OSA patients who are CPAP-intolerant, have a body mass index <32, apnea-hypopnea index <50, and without a concentric pattern of upper airway collapse on sleep endoscopy. Conclusions: Data from the STAR trial suggests that a subset of OSA patients can achieve a significant therapeutic response from hypoglossal nerve stimulation. However, these results may be limited in their generalizability to the broader OSA population. Keywords: Hypoglossal nerve stimulation, Obstructive sleep apnea, Upper airway stimulation, CPAP-intolerant, Neurostimulation |
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