Mechanisms of CNS Viral Seeding by HIV<sup>+</sup> CD14<sup>+</sup> CD16<sup>+</sup> Monocytes: Establishment and Reseeding of Viral Reservoirs Contributing to HIV-Associated Neurocognitive Disorders

Mechanisms of CNS Viral Seeding by HIV<sup>+</sup> CD14<sup>+</sup> CD16<sup>+</sup> Monocytes: Establishment and Reseeding of Viral Reservoirs Contributing to HIV-Associated Neurocognitive Disorders

ABSTRACT HIV reservoirs persist despite antiretroviral therapy (ART) and are established within a few days after infection. Infected myeloid cells in the central nervous system (CNS) may contribute to the establishment of a CNS viral reservoir. The mature CD14+ CD16+ monocyte subset enters the CNS i...

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Bibliographic Details
Main Authors: Mike Veenstra, Rosiris León-Rivera, Ming Li, Lucio Gama, Janice E. Clements, Joan W. Berman
Format: article
Language:EN
Published: American Society for Microbiology 2017
Subjects:
CNS
HIV
cognition
qPCR
reservoirs
Microbiology
QR1-502
Online Access:https://doaj.org/article/8981c6ce8a9c42c997d3b35fb6bf5e49
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https://doaj.org/article/8981c6ce8a9c42c997d3b35fb6bf5e49

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