Mechanisms of CNS Viral Seeding by HIV<sup>+</sup> CD14<sup>+</sup> CD16<sup>+</sup> Monocytes: Establishment and Reseeding of Viral Reservoirs Contributing to HIV-Associated Neurocognitive Disorders
ABSTRACT HIV reservoirs persist despite antiretroviral therapy (ART) and are established within a few days after infection. Infected myeloid cells in the central nervous system (CNS) may contribute to the establishment of a CNS viral reservoir. The mature CD14+ CD16+ monocyte subset enters the CNS i...
Saved in:
Main Authors: | Mike Veenstra, Rosiris León-Rivera, Ming Li, Lucio Gama, Janice E. Clements, Joan W. Berman |
---|---|
Format: | article |
Language: | EN |
Published: |
American Society for Microbiology
2017
|
Subjects: | |
Online Access: | https://doaj.org/article/8981c6ce8a9c42c997d3b35fb6bf5e49 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
CD161<sup>+</sup> CD4<sup>+</sup> T Cells Harbor Clonally Expanded Replication-Competent HIV-1 in Antiretroviral Therapy-Suppressed Individuals
by: Xiaomin Li, et al.
Published: (2019) -
Phenotype remodeling in neutrophilic granulocyte subsets CD64<sup>-</sup>CD32<sup>+</sup>CD16<sup>+</sup>CD11B<sup>+</sup>NG, CD64<sup>+</sup>CD32<sup>+</sup>CD16<sup>+</sup>CD11B<sup>+</sup>NG in <i>de novo</i> experimental model of viral-bacterial infection <i>in vitro</i>
by: I. V. Nesterova, et al.
Published: (2021) -
HIV-1 Vpu Promotes Phagocytosis of Infected CD4<sup>+</sup> T Cells by Macrophages through Downregulation of CD47
by: Lijun Cong, et al.
Published: (2021) -
DNA-Containing Immunocomplexes Promote Inflammasome Assembly and Release of Pyrogenic Cytokines by CD14<sup>+</sup> CD16<sup>+</sup> CD64<sup>high</sup> CD32<sup>low</sup> Inflammatory Monocytes from Malaria Patients
by: Isabella C. Hirako, et al.
Published: (2015) -
ESTIMATION OF LEVEL OF SUBPOPULATION CD14<sup>+</sup>/CD16<sup>+</sup> MONOCYTES IN PATIENTS WITH JUVENILE DEPRESSIONS
by: E. F. Vasilyeva, et al.
Published: (2019)