Theoretical and Simulation-Based Investigation of the Relationship between Sequencing Effort, Microbial Community Richness, and Diversity in Binning Metagenome-Assembled Genomes

ABSTRACT We applied theoretical and simulation-based approaches to characterize how microbial community structure influences the amount of sequencing effort to reconstruct metagenomes that are assembled from short-read sequences. First, a coupon collector equation was proposed as an analytical model...

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Autores principales: Taylor M. Royalty, Andrew D. Steen
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2019
Materias:
MAG
Acceso en línea:https://doaj.org/article/898938fc8c99416689f3192ea6499555
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