IL-33 expression in response to SARS-CoV-2 correlates with seropositivity in COVID-19 convalescent individuals

IL-33 expression in response to SARS-CoV-2 correlates with seropositivity in COVID-19 convalescent individuals

Our understanding of the immune response to SARS-CoV-2 infection is still incomplete. Here, the authors find that IL-33, produced during immune recall potentially by CD14+ monocytes, correlates with CD4+ T cell activation, anti-SARS-CoV-2 antibody titer, and disease severity in a cohort of convalesc...

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Autores principales: Michal A. Stanczak, David E. Sanin, Petya Apostolova, Gabriele Nerz, Dimitrios Lampaki, Maike Hofmann, Daniel Steinmann, Marvin Krohn-Grimberghe, Robert Thimme, Gerhard Mittler, Cornelius F. Waller, Edward J. Pearce, Erika L. Pearce
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Science
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Acceso en línea:https://doaj.org/article/89933778592e495dada140299ff2f8c5
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Sumario:Our understanding of the immune response to SARS-CoV-2 infection is still incomplete. Here, the authors find that IL-33, produced during immune recall potentially by CD14+ monocytes, correlates with CD4+ T cell activation, anti-SARS-CoV-2 antibody titer, and disease severity in a cohort of convalescent individuals professionally exposed to the virus.

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