IL-33 expression in response to SARS-CoV-2 correlates with seropositivity in COVID-19 convalescent individuals

Our understanding of the immune response to SARS-CoV-2 infection is still incomplete. Here, the authors find that IL-33, produced during immune recall potentially by CD14+ monocytes, correlates with CD4+ T cell activation, anti-SARS-CoV-2 antibody titer, and disease severity in a cohort of convalesc...

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Autores principales:	Michal A. Stanczak, David E. Sanin, Petya Apostolova, Gabriele Nerz, Dimitrios Lampaki, Maike Hofmann, Daniel Steinmann, Marvin Krohn-Grimberghe, Robert Thimme, Gerhard Mittler, Cornelius F. Waller, Edward J. Pearce, Erika L. Pearce
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/89933778592e495dada140299ff2f8c5
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spelling	oai:doaj.org-article:89933778592e495dada140299ff2f8c52021-12-02T14:37:45ZIL-33 expression in response to SARS-CoV-2 correlates with seropositivity in COVID-19 convalescent individuals10.1038/s41467-021-22449-w2041-1723https://doaj.org/article/89933778592e495dada140299ff2f8c52021-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22449-whttps://doaj.org/toc/2041-1723Our understanding of the immune response to SARS-CoV-2 infection is still incomplete. Here, the authors find that IL-33, produced during immune recall potentially by CD14+ monocytes, correlates with CD4+ T cell activation, anti-SARS-CoV-2 antibody titer, and disease severity in a cohort of convalescent individuals professionally exposed to the virus.Michal A. StanczakDavid E. SaninPetya ApostolovaGabriele NerzDimitrios LampakiMaike HofmannDaniel SteinmannMarvin Krohn-GrimbergheRobert ThimmeGerhard MittlerCornelius F. WallerEdward J. PearceErika L. PearceNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Michal A. Stanczak David E. Sanin Petya Apostolova Gabriele Nerz Dimitrios Lampaki Maike Hofmann Daniel Steinmann Marvin Krohn-Grimberghe Robert Thimme Gerhard Mittler Cornelius F. Waller Edward J. Pearce Erika L. Pearce IL-33 expression in response to SARS-CoV-2 correlates with seropositivity in COVID-19 convalescent individuals
description	Our understanding of the immune response to SARS-CoV-2 infection is still incomplete. Here, the authors find that IL-33, produced during immune recall potentially by CD14+ monocytes, correlates with CD4+ T cell activation, anti-SARS-CoV-2 antibody titer, and disease severity in a cohort of convalescent individuals professionally exposed to the virus.
format	article
author	Michal A. Stanczak David E. Sanin Petya Apostolova Gabriele Nerz Dimitrios Lampaki Maike Hofmann Daniel Steinmann Marvin Krohn-Grimberghe Robert Thimme Gerhard Mittler Cornelius F. Waller Edward J. Pearce Erika L. Pearce
author_facet	Michal A. Stanczak David E. Sanin Petya Apostolova Gabriele Nerz Dimitrios Lampaki Maike Hofmann Daniel Steinmann Marvin Krohn-Grimberghe Robert Thimme Gerhard Mittler Cornelius F. Waller Edward J. Pearce Erika L. Pearce
author_sort	Michal A. Stanczak
title	IL-33 expression in response to SARS-CoV-2 correlates with seropositivity in COVID-19 convalescent individuals
title_short	IL-33 expression in response to SARS-CoV-2 correlates with seropositivity in COVID-19 convalescent individuals
title_full	IL-33 expression in response to SARS-CoV-2 correlates with seropositivity in COVID-19 convalescent individuals
title_fullStr	IL-33 expression in response to SARS-CoV-2 correlates with seropositivity in COVID-19 convalescent individuals
title_full_unstemmed	IL-33 expression in response to SARS-CoV-2 correlates with seropositivity in COVID-19 convalescent individuals
title_sort	il-33 expression in response to sars-cov-2 correlates with seropositivity in covid-19 convalescent individuals
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/89933778592e495dada140299ff2f8c5
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IL-33 expression in response to SARS-CoV-2 correlates with seropositivity in COVID-19 convalescent individuals

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