Assessing capacity to consent for research in cognitively impaired older patients

Thomas Gilbert,1 Antoine Bosquet,2 Catherine Thomas-Antérion,3,4 Marc Bonnefoy,1 Olivia Le Saux1 1Geriatric Department, Hospices Civils de Lyon, Lyon Sud Hospital, Pierre-Bénite, France; 2Internal Medicine Unit, AP-HP – Louis Mourier Hospital, Colombes, France; 3Plei...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Gilbert T, Bosquet A, Thomas-Antérion C, Bonnefoy M, Le Saux O
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2017
Materias:	aged assessment tools clinical research decision-making capacity Geriatrics RC952-954.6
Acceso en línea:	https://doaj.org/article/89a1ac5810dd454d99c1effbc3902cde
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:89a1ac5810dd454d99c1effbc3902cde
record_format	dspace
spelling	oai:doaj.org-article:89a1ac5810dd454d99c1effbc3902cde2021-12-02T02:16:25ZAssessing capacity to consent for research in cognitively impaired older patients1178-1998https://doaj.org/article/89a1ac5810dd454d99c1effbc3902cde2017-09-01T00:00:00Zhttps://www.dovepress.com/assessing-capacity-to-consent-for-research-in-cognitively-impaired-old-peer-reviewed-article-CIAhttps://doaj.org/toc/1178-1998Thomas Gilbert,1 Antoine Bosquet,2 Catherine Thomas-Antérion,3,4 Marc Bonnefoy,1 Olivia Le Saux1 1Geriatric Department, Hospices Civils de Lyon, Lyon Sud Hospital, Pierre-Bénite, France; 2Internal Medicine Unit, AP-HP – Louis Mourier Hospital, Colombes, France; 3Plein Ciel, Lyon, France; 4Laboratory for the Study of Cognitive Mechanisms, Lyon 2 University, Lyon, France Background: The number of clinical trials including older patients, and particularly patients with cognitive impairment, is increasing. While statutory provisions exist to make sure that the capacity to consent is assessed systematically for each patient, many gray areas remain with regard to how this assessment is made or should be made in the routine practice of clinical research. Objectives: The aim of this review was to draw up an inventory of assessment tools evaluating older patients’ capacity to consent specifically applicable to clinical research, which could be used in routine practice. Methods: Two authors independently searched PubMed, Cochrane, and Google Scholar databases between November 2015 and January 2016. The search was actualized in April 2017. We used keywords (MeSH terms and text words) referring to informed consent, capacity to consent, consent for research, research ethics, cognitive impairment, vulnerable older patients, and assessment tools. Existing reviews were also considered. Results: Among the numerous existing tools for assessing capacity to consent, 14 seemed potentially suited for clinical research and six were evaluated in older patients. The MacArthur Competence Assessment Tool for Clinical Research (MacCAT-CR) was the most frequently cited. Conclusion: The MacCAT-CR is currently the most used and the best validated questionnaire. However, it appears difficult to use and time-consuming. A more recent tool, the University of California Brief Assessment of Capacity to Consent (UBACC), seems interesting for routine practice because of its simplicity, relevance, and applicability in older patients. Keywords: aged, assessment tools, clinical research, decision-making capacityGilbert TBosquet AThomas-Antérion CBonnefoy MLe Saux ODove Medical Pressarticleagedassessment toolsclinical researchdecision-making capacityGeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 12, Pp 1553-1563 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	aged assessment tools clinical research decision-making capacity Geriatrics RC952-954.6
spellingShingle	aged assessment tools clinical research decision-making capacity Geriatrics RC952-954.6 Gilbert T Bosquet A Thomas-Antérion C Bonnefoy M Le Saux O Assessing capacity to consent for research in cognitively impaired older patients
description	Thomas Gilbert,1 Antoine Bosquet,2 Catherine Thomas-Antérion,3,4 Marc Bonnefoy,1 Olivia Le Saux1 1Geriatric Department, Hospices Civils de Lyon, Lyon Sud Hospital, Pierre-Bénite, France; 2Internal Medicine Unit, AP-HP – Louis Mourier Hospital, Colombes, France; 3Plein Ciel, Lyon, France; 4Laboratory for the Study of Cognitive Mechanisms, Lyon 2 University, Lyon, France Background: The number of clinical trials including older patients, and particularly patients with cognitive impairment, is increasing. While statutory provisions exist to make sure that the capacity to consent is assessed systematically for each patient, many gray areas remain with regard to how this assessment is made or should be made in the routine practice of clinical research. Objectives: The aim of this review was to draw up an inventory of assessment tools evaluating older patients’ capacity to consent specifically applicable to clinical research, which could be used in routine practice. Methods: Two authors independently searched PubMed, Cochrane, and Google Scholar databases between November 2015 and January 2016. The search was actualized in April 2017. We used keywords (MeSH terms and text words) referring to informed consent, capacity to consent, consent for research, research ethics, cognitive impairment, vulnerable older patients, and assessment tools. Existing reviews were also considered. Results: Among the numerous existing tools for assessing capacity to consent, 14 seemed potentially suited for clinical research and six were evaluated in older patients. The MacArthur Competence Assessment Tool for Clinical Research (MacCAT-CR) was the most frequently cited. Conclusion: The MacCAT-CR is currently the most used and the best validated questionnaire. However, it appears difficult to use and time-consuming. A more recent tool, the University of California Brief Assessment of Capacity to Consent (UBACC), seems interesting for routine practice because of its simplicity, relevance, and applicability in older patients. Keywords: aged, assessment tools, clinical research, decision-making capacity
format	article
author	Gilbert T Bosquet A Thomas-Antérion C Bonnefoy M Le Saux O
author_facet	Gilbert T Bosquet A Thomas-Antérion C Bonnefoy M Le Saux O
author_sort	Gilbert T
title	Assessing capacity to consent for research in cognitively impaired older patients
title_short	Assessing capacity to consent for research in cognitively impaired older patients
title_full	Assessing capacity to consent for research in cognitively impaired older patients
title_fullStr	Assessing capacity to consent for research in cognitively impaired older patients
title_full_unstemmed	Assessing capacity to consent for research in cognitively impaired older patients
title_sort	assessing capacity to consent for research in cognitively impaired older patients
publisher	Dove Medical Press
publishDate	2017
url	https://doaj.org/article/89a1ac5810dd454d99c1effbc3902cde
work_keys_str_mv	AT gilbertt assessingcapacitytoconsentforresearchincognitivelyimpairedolderpatients AT bosqueta assessingcapacitytoconsentforresearchincognitivelyimpairedolderpatients AT thomasanterionc assessingcapacitytoconsentforresearchincognitivelyimpairedolderpatients AT bonnefoym assessingcapacitytoconsentforresearchincognitivelyimpairedolderpatients AT lesauxo assessingcapacitytoconsentforresearchincognitivelyimpairedolderpatients
_version_	1718402607417917440

Assessing capacity to consent for research in cognitively impaired older patients

Ejemplares similares