Gene expression profiling identifies HOXB4 as a direct downstream target of GATA-2 in human CD34+ hematopoietic cells.
Aplastic anemia is characterized by a reduced hematopoietic stem cell number. Although GATA-2 expression was reported to be decreased in CD34-positive cells in aplastic anemia, many questions remain regarding the intrinsic characteristics of hematopoietic stem cells in this disease. In this study, w...
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Auteurs principaux: | , , , , , , , , , , |
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Format: | article |
Langue: | EN |
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Public Library of Science (PLoS)
2012
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Accès en ligne: | https://doaj.org/article/89a61d1a175b4d46bb5440315f06d2d5 |
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