Epigenetic responses in juvenile Lemon sharks (Negaprion brevirostris) during a coastal dredging episode in Bimini, Bahamas

Sharks serve as key predators in coastal areas, with several species using near shore habitats as nursery refuges. With many shark species threatened or endangered, it is now critical to increase the knowledge of how anthropogenic activities impact these populations. This study is the first attempt...

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Autores principales:	Andria Paige Beal, Serena Hackerott, Bryan Franks, Samuel H Gruber, Kevin Feldheim, Jose M Eirin-Lopez
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2021
Materias:	Ecology QH540-549.5
Acceso en línea:	https://doaj.org/article/89a78afca31542708592a3f54ffe1ef7
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spelling	oai:doaj.org-article:89a78afca31542708592a3f54ffe1ef72021-12-01T04:53:44ZEpigenetic responses in juvenile Lemon sharks (Negaprion brevirostris) during a coastal dredging episode in Bimini, Bahamas1470-160X10.1016/j.ecolind.2021.107793https://doaj.org/article/89a78afca31542708592a3f54ffe1ef72021-08-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S1470160X21004581https://doaj.org/toc/1470-160XSharks serve as key predators in coastal areas, with several species using near shore habitats as nursery refuges. With many shark species threatened or endangered, it is now critical to increase the knowledge of how anthropogenic activities impact these populations. This study is the first attempt at characterizing epigenetic modifications in elasmobranchs, and their potential as biomarkers of stress and disease using a dredging event episode in the early 2000′s in Bimini, Bahamas, as a model system. Lemon shark fin samples were selected from a historic archive (1995–2012) of Bimini’s North (impacted) and South (control) shark nurseries, and classified as before (1995–2000), during (2001–2006), and after (2007–2012) the dredging event. Genome-wide DNA methylation was analyzed in these samples, along with the quantification of trace metals to investigate temporal and spatial patterns of metal concentrations. The obtained results revealed differential DNA methylation patterns in sharks from the North nursery (closest to the dredging site). While low concentrations of metals were found for all nursery sites and time frames, one trace metal (Manganese) was significantly correlated with the observed differences in DNA methylation. Overall, the findings of this study support DNA methylation as a potential stress biomarker for sharks, even in the absence of a reference genome. Furthermore, the identification of genomic regions differentially methylated in response to stress provides a basis for future analyses aimed at identifying gene networks and subsequent physiological responses to these events. Collectively, these analyses will help improve shark population monitoring, management, and conservation in impacted areas.Andria Paige BealSerena HackerottBryan FranksSamuel H GruberKevin FeldheimJose M Eirin-LopezElsevierarticleEcologyQH540-549.5ENEcological Indicators, Vol 127, Iss , Pp 107793- (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ecology QH540-549.5
spellingShingle	Ecology QH540-549.5 Andria Paige Beal Serena Hackerott Bryan Franks Samuel H Gruber Kevin Feldheim Jose M Eirin-Lopez Epigenetic responses in juvenile Lemon sharks (Negaprion brevirostris) during a coastal dredging episode in Bimini, Bahamas
description	Sharks serve as key predators in coastal areas, with several species using near shore habitats as nursery refuges. With many shark species threatened or endangered, it is now critical to increase the knowledge of how anthropogenic activities impact these populations. This study is the first attempt at characterizing epigenetic modifications in elasmobranchs, and their potential as biomarkers of stress and disease using a dredging event episode in the early 2000′s in Bimini, Bahamas, as a model system. Lemon shark fin samples were selected from a historic archive (1995–2012) of Bimini’s North (impacted) and South (control) shark nurseries, and classified as before (1995–2000), during (2001–2006), and after (2007–2012) the dredging event. Genome-wide DNA methylation was analyzed in these samples, along with the quantification of trace metals to investigate temporal and spatial patterns of metal concentrations. The obtained results revealed differential DNA methylation patterns in sharks from the North nursery (closest to the dredging site). While low concentrations of metals were found for all nursery sites and time frames, one trace metal (Manganese) was significantly correlated with the observed differences in DNA methylation. Overall, the findings of this study support DNA methylation as a potential stress biomarker for sharks, even in the absence of a reference genome. Furthermore, the identification of genomic regions differentially methylated in response to stress provides a basis for future analyses aimed at identifying gene networks and subsequent physiological responses to these events. Collectively, these analyses will help improve shark population monitoring, management, and conservation in impacted areas.
format	article
author	Andria Paige Beal Serena Hackerott Bryan Franks Samuel H Gruber Kevin Feldheim Jose M Eirin-Lopez
author_facet	Andria Paige Beal Serena Hackerott Bryan Franks Samuel H Gruber Kevin Feldheim Jose M Eirin-Lopez
author_sort	Andria Paige Beal
title	Epigenetic responses in juvenile Lemon sharks (Negaprion brevirostris) during a coastal dredging episode in Bimini, Bahamas
title_short	Epigenetic responses in juvenile Lemon sharks (Negaprion brevirostris) during a coastal dredging episode in Bimini, Bahamas
title_full	Epigenetic responses in juvenile Lemon sharks (Negaprion brevirostris) during a coastal dredging episode in Bimini, Bahamas
title_fullStr	Epigenetic responses in juvenile Lemon sharks (Negaprion brevirostris) during a coastal dredging episode in Bimini, Bahamas
title_full_unstemmed	Epigenetic responses in juvenile Lemon sharks (Negaprion brevirostris) during a coastal dredging episode in Bimini, Bahamas
title_sort	epigenetic responses in juvenile lemon sharks (negaprion brevirostris) during a coastal dredging episode in bimini, bahamas
publisher	Elsevier
publishDate	2021
url	https://doaj.org/article/89a78afca31542708592a3f54ffe1ef7
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Epigenetic responses in juvenile Lemon sharks (Negaprion brevirostris) during a coastal dredging episode in Bimini, Bahamas

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