Tumor development, growth characteristics and spectrum of genetic aberrations in the TH-MYCN mouse model of neuroblastoma.

<h4>Background</h4>The TH-MYCN transgenic neuroblastoma model, with targeted MYCN expression to the developing neural crest, has been used to study neuroblastoma development and evaluate novel targeted tumor therapies.<h4>Methods</h4>We followed tumor development in 395 TH-MY...

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Autores principales: Agnes Rasmuson, Lova Segerström, Maria Nethander, Jennie Finnman, Lotta H M Elfman, Niloufar Javanmardi, Staffan Nilsson, John Inge Johnsen, Tommy Martinsson, Per Kogner
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/89af299f753e489b805ad0201041887c
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