Tumor development, growth characteristics and spectrum of genetic aberrations in the TH-MYCN mouse model of neuroblastoma.
<h4>Background</h4>The TH-MYCN transgenic neuroblastoma model, with targeted MYCN expression to the developing neural crest, has been used to study neuroblastoma development and evaluate novel targeted tumor therapies.<h4>Methods</h4>We followed tumor development in 395 TH-MY...
Guardado en:
Autores principales: | Agnes Rasmuson, Lova Segerström, Maria Nethander, Jennie Finnman, Lotta H M Elfman, Niloufar Javanmardi, Staffan Nilsson, John Inge Johnsen, Tommy Martinsson, Per Kogner |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2012
|
Materias: | |
Acceso en línea: | https://doaj.org/article/89af299f753e489b805ad0201041887c |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
MYCN amplification and ATRX mutations are incompatible in neuroblastoma
por: Maged Zeineldin, et al.
Publicado: (2020) -
An ALYREF-MYCN coactivator complex drives neuroblastoma tumorigenesis through effects on USP3 and MYCN stability
por: Zsuzsanna Nagy, et al.
Publicado: (2021) -
Enhancer hijacking determines extrachromosomal circular MYCN amplicon architecture in neuroblastoma
por: Konstantin Helmsauer, et al.
Publicado: (2020) -
High Expression of <i>PPM1D</i> Induces Tumors Phenotypically Similar to <i>TP53</i> Loss-of-Function Mutations in Mice
por: Jelena Milosevic, et al.
Publicado: (2021) -
Whole-genome sequencing of recurrent neuroblastoma reveals somatic mutations that affect key players in cancer progression and telomere maintenance
por: Susanne Fransson, et al.
Publicado: (2020)