Rho-GTPase pathways may differentiate treatment response to TNF-alpha and IL-17A inhibitors in psoriatic arthritis
Abstract Biological therapies have dramatically improved the therapeutic landscape of psoriatic arthritis (PsA); however, 40–50% of patients are primary non-responders with response rates declining significantly with each successive biological therapy. Therefore, there is a pressing need to develop...
Guardado en:
Autores principales: | Sara Rahmati, Darren D. O’Rielly, Quan Li, Dianne Codner, Amanda Dohey, Kari Jenkins, Igor Jurisica, Dafna D. Gladman, Vinod Chandran, Proton Rahman |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
|
Materias: | |
Acceso en línea: | https://doaj.org/article/89afa7b431d842f397da1b39a9b64a04 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Genome-wide signatures of 'rearrangement hotspots' within segmental duplications in humans.
por: Mohammed Uddin, et al.
Publicado: (2011) -
Selectivity Determinants of RHO GTPase Binding to IQGAPs
por: Niloufar Mosaddeghzadeh, et al.
Publicado: (2021) -
Rho GTPases in Skeletal Muscle Development and Homeostasis
por: Sonia Rodríguez-Fdez, et al.
Publicado: (2021) -
The Role of Rho-GTPases and actin polymerization during Macrophage Tunneling Nanotube Biogenesis
por: Samer J. Hanna, et al.
Publicado: (2017) -
RHO GTPase-Related Long Noncoding RNAs in Human Cancers
por: Mahsa Saliani, et al.
Publicado: (2021)