METTL3 is essential for postnatal development of brown adipose tissue and energy expenditure in mice

N6-methyladenosine (m6A) is one of the most prevalent mRNA modifications in eukaryotes. Here the authors show that the m6A writer protein methyltransferase-like (METTL) 3 plays an important role for the development of brown adipose tissue.

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Autores principales: Yuqin Wang, Ming Gao, Fuxing Zhu, Xinzhi Li, Ying Yang, Qiuxin Yan, Linna Jia, Liwei Xie, Zheng Chen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/89afae99cf9d4cde96210d96ab2ea0b3
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Sumario:N6-methyladenosine (m6A) is one of the most prevalent mRNA modifications in eukaryotes. Here the authors show that the m6A writer protein methyltransferase-like (METTL) 3 plays an important role for the development of brown adipose tissue.