METTL3 is essential for postnatal development of brown adipose tissue and energy expenditure in mice

N6-methyladenosine (m6A) is one of the most prevalent mRNA modifications in eukaryotes. Here the authors show that the m6A writer protein methyltransferase-like (METTL) 3 plays an important role for the development of brown adipose tissue.

Guardado en:
Detalles Bibliográficos
Autores principales: Yuqin Wang, Ming Gao, Fuxing Zhu, Xinzhi Li, Ying Yang, Qiuxin Yan, Linna Jia, Liwei Xie, Zheng Chen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
Materias:
Q
Acceso en línea:https://doaj.org/article/89afae99cf9d4cde96210d96ab2ea0b3
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:89afae99cf9d4cde96210d96ab2ea0b3
record_format dspace
spelling oai:doaj.org-article:89afae99cf9d4cde96210d96ab2ea0b32021-12-02T16:50:03ZMETTL3 is essential for postnatal development of brown adipose tissue and energy expenditure in mice10.1038/s41467-020-15488-22041-1723https://doaj.org/article/89afae99cf9d4cde96210d96ab2ea0b32020-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15488-2https://doaj.org/toc/2041-1723N6-methyladenosine (m6A) is one of the most prevalent mRNA modifications in eukaryotes. Here the authors show that the m6A writer protein methyltransferase-like (METTL) 3 plays an important role for the development of brown adipose tissue.Yuqin WangMing GaoFuxing ZhuXinzhi LiYing YangQiuxin YanLinna JiaLiwei XieZheng ChenNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Yuqin Wang
Ming Gao
Fuxing Zhu
Xinzhi Li
Ying Yang
Qiuxin Yan
Linna Jia
Liwei Xie
Zheng Chen
METTL3 is essential for postnatal development of brown adipose tissue and energy expenditure in mice
description N6-methyladenosine (m6A) is one of the most prevalent mRNA modifications in eukaryotes. Here the authors show that the m6A writer protein methyltransferase-like (METTL) 3 plays an important role for the development of brown adipose tissue.
format article
author Yuqin Wang
Ming Gao
Fuxing Zhu
Xinzhi Li
Ying Yang
Qiuxin Yan
Linna Jia
Liwei Xie
Zheng Chen
author_facet Yuqin Wang
Ming Gao
Fuxing Zhu
Xinzhi Li
Ying Yang
Qiuxin Yan
Linna Jia
Liwei Xie
Zheng Chen
author_sort Yuqin Wang
title METTL3 is essential for postnatal development of brown adipose tissue and energy expenditure in mice
title_short METTL3 is essential for postnatal development of brown adipose tissue and energy expenditure in mice
title_full METTL3 is essential for postnatal development of brown adipose tissue and energy expenditure in mice
title_fullStr METTL3 is essential for postnatal development of brown adipose tissue and energy expenditure in mice
title_full_unstemmed METTL3 is essential for postnatal development of brown adipose tissue and energy expenditure in mice
title_sort mettl3 is essential for postnatal development of brown adipose tissue and energy expenditure in mice
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/89afae99cf9d4cde96210d96ab2ea0b3
work_keys_str_mv AT yuqinwang mettl3isessentialforpostnataldevelopmentofbrownadiposetissueandenergyexpenditureinmice
AT minggao mettl3isessentialforpostnataldevelopmentofbrownadiposetissueandenergyexpenditureinmice
AT fuxingzhu mettl3isessentialforpostnataldevelopmentofbrownadiposetissueandenergyexpenditureinmice
AT xinzhili mettl3isessentialforpostnataldevelopmentofbrownadiposetissueandenergyexpenditureinmice
AT yingyang mettl3isessentialforpostnataldevelopmentofbrownadiposetissueandenergyexpenditureinmice
AT qiuxinyan mettl3isessentialforpostnataldevelopmentofbrownadiposetissueandenergyexpenditureinmice
AT linnajia mettl3isessentialforpostnataldevelopmentofbrownadiposetissueandenergyexpenditureinmice
AT liweixie mettl3isessentialforpostnataldevelopmentofbrownadiposetissueandenergyexpenditureinmice
AT zhengchen mettl3isessentialforpostnataldevelopmentofbrownadiposetissueandenergyexpenditureinmice
_version_ 1718383110340476928