METTL3 is essential for postnatal development of brown adipose tissue and energy expenditure in mice
N6-methyladenosine (m6A) is one of the most prevalent mRNA modifications in eukaryotes. Here the authors show that the m6A writer protein methyltransferase-like (METTL) 3 plays an important role for the development of brown adipose tissue.
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Nature Portfolio
2020
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oai:doaj.org-article:89afae99cf9d4cde96210d96ab2ea0b32021-12-02T16:50:03ZMETTL3 is essential for postnatal development of brown adipose tissue and energy expenditure in mice10.1038/s41467-020-15488-22041-1723https://doaj.org/article/89afae99cf9d4cde96210d96ab2ea0b32020-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15488-2https://doaj.org/toc/2041-1723N6-methyladenosine (m6A) is one of the most prevalent mRNA modifications in eukaryotes. Here the authors show that the m6A writer protein methyltransferase-like (METTL) 3 plays an important role for the development of brown adipose tissue.Yuqin WangMing GaoFuxing ZhuXinzhi LiYing YangQiuxin YanLinna JiaLiwei XieZheng ChenNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020) |
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Science Q Yuqin Wang Ming Gao Fuxing Zhu Xinzhi Li Ying Yang Qiuxin Yan Linna Jia Liwei Xie Zheng Chen METTL3 is essential for postnatal development of brown adipose tissue and energy expenditure in mice |
description |
N6-methyladenosine (m6A) is one of the most prevalent mRNA modifications in eukaryotes. Here the authors show that the m6A writer protein methyltransferase-like (METTL) 3 plays an important role for the development of brown adipose tissue. |
format |
article |
author |
Yuqin Wang Ming Gao Fuxing Zhu Xinzhi Li Ying Yang Qiuxin Yan Linna Jia Liwei Xie Zheng Chen |
author_facet |
Yuqin Wang Ming Gao Fuxing Zhu Xinzhi Li Ying Yang Qiuxin Yan Linna Jia Liwei Xie Zheng Chen |
author_sort |
Yuqin Wang |
title |
METTL3 is essential for postnatal development of brown adipose tissue and energy expenditure in mice |
title_short |
METTL3 is essential for postnatal development of brown adipose tissue and energy expenditure in mice |
title_full |
METTL3 is essential for postnatal development of brown adipose tissue and energy expenditure in mice |
title_fullStr |
METTL3 is essential for postnatal development of brown adipose tissue and energy expenditure in mice |
title_full_unstemmed |
METTL3 is essential for postnatal development of brown adipose tissue and energy expenditure in mice |
title_sort |
mettl3 is essential for postnatal development of brown adipose tissue and energy expenditure in mice |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/89afae99cf9d4cde96210d96ab2ea0b3 |
work_keys_str_mv |
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