In vivo Serial Passaging of Human–Simian Immunodeficiency Virus Clones Identifies Characteristics for Persistent Viral Replication

We previously reported that a human immunodeficiency virus type 1 with a simian immunodeficiency virus vif substitution (HSIV-vifNL4-3) could replicate in pigtailed macaques (PTMs), demonstrating that Vif is a species-specific tropism factor of primate lentiviruses. However, infections did not resul...

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Autores principales: Rajesh Thippeshappa, Patricia Polacino, Shaswath S. Chandrasekar, Khanghy Truong, Anisha Misra, Paula C. Aulicino, Shiu-Lok Hu, Deepak Kaushal, Jason T. Kimata
Formato: article
Lenguaje:EN
Publicado: Frontiers Media S.A. 2021
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Acceso en línea:https://doaj.org/article/89b431c456c245b6913d3f3f0bc88295
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