An investigation of irreproducibility in maximum likelihood phylogenetic inference

Replicate runs of maximum likelihood phylogenetic analyses can generate different tree topologies due to differences in parameters, such as random seeds. Here, Shen et al. demonstrate that replicate runs can generate substantially different tree topologies even with identical data and parameters.

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Autores principales:	Xing-Xing Shen, Yuanning Li, Chris Todd Hittinger, Xue-xin Chen, Antonis Rokas
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/89b812f2f7b64fb78541099c22294c84
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spelling	oai:doaj.org-article:89b812f2f7b64fb78541099c22294c842021-12-02T14:42:49ZAn investigation of irreproducibility in maximum likelihood phylogenetic inference10.1038/s41467-020-20005-62041-1723https://doaj.org/article/89b812f2f7b64fb78541099c22294c842020-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20005-6https://doaj.org/toc/2041-1723Replicate runs of maximum likelihood phylogenetic analyses can generate different tree topologies due to differences in parameters, such as random seeds. Here, Shen et al. demonstrate that replicate runs can generate substantially different tree topologies even with identical data and parameters.Xing-Xing ShenYuanning LiChris Todd HittingerXue-xin ChenAntonis RokasNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Xing-Xing Shen Yuanning Li Chris Todd Hittinger Xue-xin Chen Antonis Rokas An investigation of irreproducibility in maximum likelihood phylogenetic inference
description	Replicate runs of maximum likelihood phylogenetic analyses can generate different tree topologies due to differences in parameters, such as random seeds. Here, Shen et al. demonstrate that replicate runs can generate substantially different tree topologies even with identical data and parameters.
format	article
author	Xing-Xing Shen Yuanning Li Chris Todd Hittinger Xue-xin Chen Antonis Rokas
author_facet	Xing-Xing Shen Yuanning Li Chris Todd Hittinger Xue-xin Chen Antonis Rokas
author_sort	Xing-Xing Shen
title	An investigation of irreproducibility in maximum likelihood phylogenetic inference
title_short	An investigation of irreproducibility in maximum likelihood phylogenetic inference
title_full	An investigation of irreproducibility in maximum likelihood phylogenetic inference
title_fullStr	An investigation of irreproducibility in maximum likelihood phylogenetic inference
title_full_unstemmed	An investigation of irreproducibility in maximum likelihood phylogenetic inference
title_sort	investigation of irreproducibility in maximum likelihood phylogenetic inference
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/89b812f2f7b64fb78541099c22294c84
work_keys_str_mv	AT xingxingshen aninvestigationofirreproducibilityinmaximumlikelihoodphylogeneticinference AT yuanningli aninvestigationofirreproducibilityinmaximumlikelihoodphylogeneticinference AT christoddhittinger aninvestigationofirreproducibilityinmaximumlikelihoodphylogeneticinference AT xuexinchen aninvestigationofirreproducibilityinmaximumlikelihoodphylogeneticinference AT antonisrokas aninvestigationofirreproducibilityinmaximumlikelihoodphylogeneticinference AT xingxingshen investigationofirreproducibilityinmaximumlikelihoodphylogeneticinference AT yuanningli investigationofirreproducibilityinmaximumlikelihoodphylogeneticinference AT christoddhittinger investigationofirreproducibilityinmaximumlikelihoodphylogeneticinference AT xuexinchen investigationofirreproducibilityinmaximumlikelihoodphylogeneticinference AT antonisrokas investigationofirreproducibilityinmaximumlikelihoodphylogeneticinference
_version_	1718389581430128640

An investigation of irreproducibility in maximum likelihood phylogenetic inference

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