A minimal biochemical route towards de novo formation of synthetic phospholipid membranes

The origin of phospholipids, the primary constituents of cell membranes, is uncertain. Here, the authors develop an in vitro system to synthesize phospholipid molecules from water-soluble single-chain amphiphilic precursors via a reaction catalysed by the mycobacterial ligase FadD10.

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Autores principales:	Ahanjit Bhattacharya, Roberto J. Brea, Henrike Niederholtmeyer, Neal K. Devaraj
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/89bca9b9c80c40c190a8c51af0b8b13d
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spelling	oai:doaj.org-article:89bca9b9c80c40c190a8c51af0b8b13d2021-12-02T16:57:21ZA minimal biochemical route towards de novo formation of synthetic phospholipid membranes10.1038/s41467-018-08174-x2041-1723https://doaj.org/article/89bca9b9c80c40c190a8c51af0b8b13d2019-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-08174-xhttps://doaj.org/toc/2041-1723The origin of phospholipids, the primary constituents of cell membranes, is uncertain. Here, the authors develop an in vitro system to synthesize phospholipid molecules from water-soluble single-chain amphiphilic precursors via a reaction catalysed by the mycobacterial ligase FadD10.Ahanjit BhattacharyaRoberto J. BreaHenrike NiederholtmeyerNeal K. DevarajNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-8 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Ahanjit Bhattacharya Roberto J. Brea Henrike Niederholtmeyer Neal K. Devaraj A minimal biochemical route towards de novo formation of synthetic phospholipid membranes
description	The origin of phospholipids, the primary constituents of cell membranes, is uncertain. Here, the authors develop an in vitro system to synthesize phospholipid molecules from water-soluble single-chain amphiphilic precursors via a reaction catalysed by the mycobacterial ligase FadD10.
format	article
author	Ahanjit Bhattacharya Roberto J. Brea Henrike Niederholtmeyer Neal K. Devaraj
author_facet	Ahanjit Bhattacharya Roberto J. Brea Henrike Niederholtmeyer Neal K. Devaraj
author_sort	Ahanjit Bhattacharya
title	A minimal biochemical route towards de novo formation of synthetic phospholipid membranes
title_short	A minimal biochemical route towards de novo formation of synthetic phospholipid membranes
title_full	A minimal biochemical route towards de novo formation of synthetic phospholipid membranes
title_fullStr	A minimal biochemical route towards de novo formation of synthetic phospholipid membranes
title_full_unstemmed	A minimal biochemical route towards de novo formation of synthetic phospholipid membranes
title_sort	minimal biochemical route towards de novo formation of synthetic phospholipid membranes
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/89bca9b9c80c40c190a8c51af0b8b13d
work_keys_str_mv	AT ahanjitbhattacharya aminimalbiochemicalroutetowardsdenovoformationofsyntheticphospholipidmembranes AT robertojbrea aminimalbiochemicalroutetowardsdenovoformationofsyntheticphospholipidmembranes AT henrikeniederholtmeyer aminimalbiochemicalroutetowardsdenovoformationofsyntheticphospholipidmembranes AT nealkdevaraj aminimalbiochemicalroutetowardsdenovoformationofsyntheticphospholipidmembranes AT ahanjitbhattacharya minimalbiochemicalroutetowardsdenovoformationofsyntheticphospholipidmembranes AT robertojbrea minimalbiochemicalroutetowardsdenovoformationofsyntheticphospholipidmembranes AT henrikeniederholtmeyer minimalbiochemicalroutetowardsdenovoformationofsyntheticphospholipidmembranes AT nealkdevaraj minimalbiochemicalroutetowardsdenovoformationofsyntheticphospholipidmembranes
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A minimal biochemical route towards de novo formation of synthetic phospholipid membranes

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