Molecular determinants of nephron vascular specialization in the kidney

The kidney is vascularized with highly specialized and zonated endothelial cells that are essential for its filtration function. Here, Barry et al. provide a single-cell RNA sequencing analysis of the kidney vasculature that highlights its transcriptional heterogeneity and uncovers pathways importan...

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Autores principales:	David M. Barry, Elizabeth A. McMillan, Balvir Kunar, Raphael Lis, Tuo Zhang, Tyler Lu, Edward Daniel, Masataka Yokoyama, Jesus M. Gomez-Salinero, Angara Sureshbabu, Ondine Cleaver, Annarita Di Lorenzo, Mary E. Choi, Jenny Xiang, David Redmond, Sina Y. Rabbany, Thangamani Muthukumar, Shahin Rafii
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/89ca827692df403aa71f8398b5ac7748
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spelling	oai:doaj.org-article:89ca827692df403aa71f8398b5ac77482021-12-02T14:39:19ZMolecular determinants of nephron vascular specialization in the kidney10.1038/s41467-019-12872-52041-1723https://doaj.org/article/89ca827692df403aa71f8398b5ac77482019-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12872-5https://doaj.org/toc/2041-1723The kidney is vascularized with highly specialized and zonated endothelial cells that are essential for its filtration function. Here, Barry et al. provide a single-cell RNA sequencing analysis of the kidney vasculature that highlights its transcriptional heterogeneity and uncovers pathways important for its development and function.David M. BarryElizabeth A. McMillanBalvir KunarRaphael LisTuo ZhangTyler LuEdward DanielMasataka YokoyamaJesus M. Gomez-SalineroAngara SureshbabuOndine CleaverAnnarita Di LorenzoMary E. ChoiJenny XiangDavid RedmondSina Y. RabbanyThangamani MuthukumarShahin RafiiNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q David M. Barry Elizabeth A. McMillan Balvir Kunar Raphael Lis Tuo Zhang Tyler Lu Edward Daniel Masataka Yokoyama Jesus M. Gomez-Salinero Angara Sureshbabu Ondine Cleaver Annarita Di Lorenzo Mary E. Choi Jenny Xiang David Redmond Sina Y. Rabbany Thangamani Muthukumar Shahin Rafii Molecular determinants of nephron vascular specialization in the kidney
description	The kidney is vascularized with highly specialized and zonated endothelial cells that are essential for its filtration function. Here, Barry et al. provide a single-cell RNA sequencing analysis of the kidney vasculature that highlights its transcriptional heterogeneity and uncovers pathways important for its development and function.
format	article
author	David M. Barry Elizabeth A. McMillan Balvir Kunar Raphael Lis Tuo Zhang Tyler Lu Edward Daniel Masataka Yokoyama Jesus M. Gomez-Salinero Angara Sureshbabu Ondine Cleaver Annarita Di Lorenzo Mary E. Choi Jenny Xiang David Redmond Sina Y. Rabbany Thangamani Muthukumar Shahin Rafii
author_facet	David M. Barry Elizabeth A. McMillan Balvir Kunar Raphael Lis Tuo Zhang Tyler Lu Edward Daniel Masataka Yokoyama Jesus M. Gomez-Salinero Angara Sureshbabu Ondine Cleaver Annarita Di Lorenzo Mary E. Choi Jenny Xiang David Redmond Sina Y. Rabbany Thangamani Muthukumar Shahin Rafii
author_sort	David M. Barry
title	Molecular determinants of nephron vascular specialization in the kidney
title_short	Molecular determinants of nephron vascular specialization in the kidney
title_full	Molecular determinants of nephron vascular specialization in the kidney
title_fullStr	Molecular determinants of nephron vascular specialization in the kidney
title_full_unstemmed	Molecular determinants of nephron vascular specialization in the kidney
title_sort	molecular determinants of nephron vascular specialization in the kidney
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/89ca827692df403aa71f8398b5ac7748
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Molecular determinants of nephron vascular specialization in the kidney

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