Modeling and simulation of the endogenous CYP3A induction marker 4β-hydroxycholesterol during enasidenib treatment

Yan Li,1 Jamie N Connarn,1 Jian Chen,2 Zeen Tong,2 Maria Palmisano,1 Simon Zhou1 1Translational Development and Clinical Pharmacology, Celgene Corporation, Summit, NJ, USA; 2Non-Clinical Development, Celgene Corporation, Summit, NJ, USA Background: Enasidenib (IDHIFA®, AG-221) is a first-in-...

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Bibliographic Details
Main Authors: Li Y, Connarn JN, Chen J, Tong Z, Palmisano M, Zhou S
Format: article
Language:EN
Published: Dove Medical Press 2019
Subjects:
Online Access:https://doaj.org/article/89d8c3d7c95e4600bcda76ac235acd0c
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