Using both qualitative and quantitative data in parameter identification for systems biology models

Much of the data generated in biology is qualitative, but exploiting such data to inform models of biological systems remains a challenge. Here, the authors demonstrate an approach that allows use of both quantitative and qualitative data for parameterising dynamical models.

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Auteurs principaux: Eshan D. Mitra, Raquel Dias, Richard G. Posner, William S. Hlavacek
Format: article
Langue:EN
Publié: Nature Portfolio 2018
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Accès en ligne:https://doaj.org/article/89dae6dda042447f86901a044a4f7f34
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Résumé:Much of the data generated in biology is qualitative, but exploiting such data to inform models of biological systems remains a challenge. Here, the authors demonstrate an approach that allows use of both quantitative and qualitative data for parameterising dynamical models.