Using both qualitative and quantitative data in parameter identification for systems biology models

Much of the data generated in biology is qualitative, but exploiting such data to inform models of biological systems remains a challenge. Here, the authors demonstrate an approach that allows use of both quantitative and qualitative data for parameterising dynamical models.

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Bibliographic Details
Main Authors: Eshan D. Mitra, Raquel Dias, Richard G. Posner, William S. Hlavacek
Format: article
Language:EN
Published: Nature Portfolio 2018
Subjects:
Q
Online Access:https://doaj.org/article/89dae6dda042447f86901a044a4f7f34
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Summary:Much of the data generated in biology is qualitative, but exploiting such data to inform models of biological systems remains a challenge. Here, the authors demonstrate an approach that allows use of both quantitative and qualitative data for parameterising dynamical models.