Using both qualitative and quantitative data in parameter identification for systems biology models
Much of the data generated in biology is qualitative, but exploiting such data to inform models of biological systems remains a challenge. Here, the authors demonstrate an approach that allows use of both quantitative and qualitative data for parameterising dynamical models.
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Nature Portfolio
2018
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oai:doaj.org-article:89dae6dda042447f86901a044a4f7f342021-12-02T14:39:48ZUsing both qualitative and quantitative data in parameter identification for systems biology models10.1038/s41467-018-06439-z2041-1723https://doaj.org/article/89dae6dda042447f86901a044a4f7f342018-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06439-zhttps://doaj.org/toc/2041-1723Much of the data generated in biology is qualitative, but exploiting such data to inform models of biological systems remains a challenge. Here, the authors demonstrate an approach that allows use of both quantitative and qualitative data for parameterising dynamical models.Eshan D. MitraRaquel DiasRichard G. PosnerWilliam S. HlavacekNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-8 (2018) |
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Science Q Eshan D. Mitra Raquel Dias Richard G. Posner William S. Hlavacek Using both qualitative and quantitative data in parameter identification for systems biology models |
description |
Much of the data generated in biology is qualitative, but exploiting such data to inform models of biological systems remains a challenge. Here, the authors demonstrate an approach that allows use of both quantitative and qualitative data for parameterising dynamical models. |
format |
article |
author |
Eshan D. Mitra Raquel Dias Richard G. Posner William S. Hlavacek |
author_facet |
Eshan D. Mitra Raquel Dias Richard G. Posner William S. Hlavacek |
author_sort |
Eshan D. Mitra |
title |
Using both qualitative and quantitative data in parameter identification for systems biology models |
title_short |
Using both qualitative and quantitative data in parameter identification for systems biology models |
title_full |
Using both qualitative and quantitative data in parameter identification for systems biology models |
title_fullStr |
Using both qualitative and quantitative data in parameter identification for systems biology models |
title_full_unstemmed |
Using both qualitative and quantitative data in parameter identification for systems biology models |
title_sort |
using both qualitative and quantitative data in parameter identification for systems biology models |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/89dae6dda042447f86901a044a4f7f34 |
work_keys_str_mv |
AT eshandmitra usingbothqualitativeandquantitativedatainparameteridentificationforsystemsbiologymodels AT raqueldias usingbothqualitativeandquantitativedatainparameteridentificationforsystemsbiologymodels AT richardgposner usingbothqualitativeandquantitativedatainparameteridentificationforsystemsbiologymodels AT williamshlavacek usingbothqualitativeandquantitativedatainparameteridentificationforsystemsbiologymodels |
_version_ |
1718390485184151552 |