Using both qualitative and quantitative data in parameter identification for systems biology models

Much of the data generated in biology is qualitative, but exploiting such data to inform models of biological systems remains a challenge. Here, the authors demonstrate an approach that allows use of both quantitative and qualitative data for parameterising dynamical models.

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Main Authors:	Eshan D. Mitra, Raquel Dias, Richard G. Posner, William S. Hlavacek
Format:	article
Language:	EN
Published:	Nature Portfolio 2018
Subjects:	Science Q
Online Access:	https://doaj.org/article/89dae6dda042447f86901a044a4f7f34
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spelling	oai:doaj.org-article:89dae6dda042447f86901a044a4f7f342021-12-02T14:39:48ZUsing both qualitative and quantitative data in parameter identification for systems biology models10.1038/s41467-018-06439-z2041-1723https://doaj.org/article/89dae6dda042447f86901a044a4f7f342018-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06439-zhttps://doaj.org/toc/2041-1723Much of the data generated in biology is qualitative, but exploiting such data to inform models of biological systems remains a challenge. Here, the authors demonstrate an approach that allows use of both quantitative and qualitative data for parameterising dynamical models.Eshan D. MitraRaquel DiasRichard G. PosnerWilliam S. HlavacekNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-8 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Eshan D. Mitra Raquel Dias Richard G. Posner William S. Hlavacek Using both qualitative and quantitative data in parameter identification for systems biology models
description	Much of the data generated in biology is qualitative, but exploiting such data to inform models of biological systems remains a challenge. Here, the authors demonstrate an approach that allows use of both quantitative and qualitative data for parameterising dynamical models.
format	article
author	Eshan D. Mitra Raquel Dias Richard G. Posner William S. Hlavacek
author_facet	Eshan D. Mitra Raquel Dias Richard G. Posner William S. Hlavacek
author_sort	Eshan D. Mitra
title	Using both qualitative and quantitative data in parameter identification for systems biology models
title_short	Using both qualitative and quantitative data in parameter identification for systems biology models
title_full	Using both qualitative and quantitative data in parameter identification for systems biology models
title_fullStr	Using both qualitative and quantitative data in parameter identification for systems biology models
title_full_unstemmed	Using both qualitative and quantitative data in parameter identification for systems biology models
title_sort	using both qualitative and quantitative data in parameter identification for systems biology models
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/89dae6dda042447f86901a044a4f7f34
work_keys_str_mv	AT eshandmitra usingbothqualitativeandquantitativedatainparameteridentificationforsystemsbiologymodels AT raqueldias usingbothqualitativeandquantitativedatainparameteridentificationforsystemsbiologymodels AT richardgposner usingbothqualitativeandquantitativedatainparameteridentificationforsystemsbiologymodels AT williamshlavacek usingbothqualitativeandquantitativedatainparameteridentificationforsystemsbiologymodels
_version_	1718390485184151552

Using both qualitative and quantitative data in parameter identification for systems biology models

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