Repurposing hyperpolarization‐activated cyclic nucleotide‐gated channels as a novel therapy for breast cancer
Abstract Hyperpolarization‐activated cyclic nucleotide‐gated (HCN) channels are members of the voltage‐gated cation channel family known to be expressed in the heart and central nervous system. Ivabradine, a small molecule HCN channel‐blocker, is FDA‐approved for clinical use as a heart rate‐reducin...
Guardado en:
Autores principales: | Ka‐Chun Mok, Ho Tsoi, Ellen PS Man, Man‐Hong Leung, Ka Man Chau, Lai‐San Wong, Wing‐Lok Chan, Sum‐Yin Chan, Mai‐Yee Luk, Jessie Y.W. Chan, Jackie K.M. Leung, Yolanda H.Y. Chan, Sellma Batalha, Virginia Lau, David C.W. Siu, Terence K.W. Lee, Chun Gong, Ui‐Soon Khoo |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Wiley
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/89dc802a66c04d34bba35fe0b981b854 |
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