Alantolactone induces apoptosis, promotes STAT3 glutathionylation and enhances chemosensitivity of A549 lung adenocarcinoma cells to doxorubicin via oxidative stress
Abstract Alantolactone (ALT), a sesquiterpene lactone component of Inula helenium, has been reported to exert anticancer activity in various cancers. However, the cellular targets and underlying mechanism of anticancer activity of ALT in various cancers including lung cancer has not been fully defin...
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Main Authors: | Amara Maryam, Tahir Mehmood, He Zhang, Yongming Li, Muhammad Khan, Tonghui Ma |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2017
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Online Access: | https://doaj.org/article/89e499c762aa4f9b9b34a57fad8d728c |
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