Nrf1 promotes heart regeneration and repair by regulating proteostasis and redox balance

Following injury, cells in regenerative tissues can regrow, but how they adapt to injury conditions to regenerate the tissue is unclear. Here the authors identify a stress-responsive and cardioprotective factor Nrf1 that is critical for neonatal heart regeneration.

Guardado en:

Detalles Bibliográficos
Autores principales:	Miao Cui, Ayhan Atmanli, Maria Gabriela Morales, Wei Tan, Kenian Chen, Xue Xiao, Lin Xu, Ning Liu, Rhonda Bassel-Duby, Eric N. Olson
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/89eb90c4780e4ba9b3c7d007980a5bab
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:89eb90c4780e4ba9b3c7d007980a5bab
record_format	dspace
spelling	oai:doaj.org-article:89eb90c4780e4ba9b3c7d007980a5bab2021-12-02T17:19:40ZNrf1 promotes heart regeneration and repair by regulating proteostasis and redox balance10.1038/s41467-021-25653-w2041-1723https://doaj.org/article/89eb90c4780e4ba9b3c7d007980a5bab2021-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25653-whttps://doaj.org/toc/2041-1723Following injury, cells in regenerative tissues can regrow, but how they adapt to injury conditions to regenerate the tissue is unclear. Here the authors identify a stress-responsive and cardioprotective factor Nrf1 that is critical for neonatal heart regeneration.Miao CuiAyhan AtmanliMaria Gabriela MoralesWei TanKenian ChenXue XiaoLin XuNing LiuRhonda Bassel-DubyEric N. OlsonNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Miao Cui Ayhan Atmanli Maria Gabriela Morales Wei Tan Kenian Chen Xue Xiao Lin Xu Ning Liu Rhonda Bassel-Duby Eric N. Olson Nrf1 promotes heart regeneration and repair by regulating proteostasis and redox balance
description	Following injury, cells in regenerative tissues can regrow, but how they adapt to injury conditions to regenerate the tissue is unclear. Here the authors identify a stress-responsive and cardioprotective factor Nrf1 that is critical for neonatal heart regeneration.
format	article
author	Miao Cui Ayhan Atmanli Maria Gabriela Morales Wei Tan Kenian Chen Xue Xiao Lin Xu Ning Liu Rhonda Bassel-Duby Eric N. Olson
author_facet	Miao Cui Ayhan Atmanli Maria Gabriela Morales Wei Tan Kenian Chen Xue Xiao Lin Xu Ning Liu Rhonda Bassel-Duby Eric N. Olson
author_sort	Miao Cui
title	Nrf1 promotes heart regeneration and repair by regulating proteostasis and redox balance
title_short	Nrf1 promotes heart regeneration and repair by regulating proteostasis and redox balance
title_full	Nrf1 promotes heart regeneration and repair by regulating proteostasis and redox balance
title_fullStr	Nrf1 promotes heart regeneration and repair by regulating proteostasis and redox balance
title_full_unstemmed	Nrf1 promotes heart regeneration and repair by regulating proteostasis and redox balance
title_sort	nrf1 promotes heart regeneration and repair by regulating proteostasis and redox balance
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/89eb90c4780e4ba9b3c7d007980a5bab
work_keys_str_mv	AT miaocui nrf1promotesheartregenerationandrepairbyregulatingproteostasisandredoxbalance AT ayhanatmanli nrf1promotesheartregenerationandrepairbyregulatingproteostasisandredoxbalance AT mariagabrielamorales nrf1promotesheartregenerationandrepairbyregulatingproteostasisandredoxbalance AT weitan nrf1promotesheartregenerationandrepairbyregulatingproteostasisandredoxbalance AT kenianchen nrf1promotesheartregenerationandrepairbyregulatingproteostasisandredoxbalance AT xuexiao nrf1promotesheartregenerationandrepairbyregulatingproteostasisandredoxbalance AT linxu nrf1promotesheartregenerationandrepairbyregulatingproteostasisandredoxbalance AT ningliu nrf1promotesheartregenerationandrepairbyregulatingproteostasisandredoxbalance AT rhondabasselduby nrf1promotesheartregenerationandrepairbyregulatingproteostasisandredoxbalance AT ericnolson nrf1promotesheartregenerationandrepairbyregulatingproteostasisandredoxbalance
_version_	1718381037323550720

Nrf1 promotes heart regeneration and repair by regulating proteostasis and redox balance

Ejemplares similares