Manganese-mediated reductive functionalization of activated aliphatic acids and primary amines

Alkyl carboxylic acids and primary amines are ubiquitous and useful for synthesis of new compounds. Here, the authors report a manganese-mediated reductive decarboxylative/deaminative functionalization of activated aliphatic acids and primary amines for construction of C-C and C-X bonds under mild c...

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Bibliographic Details
Main Authors: Zhan Li, Ke-Feng Wang, Xin Zhao, Huihui Ti, Xu-Ge Liu, Honggen Wang
Format: article
Language:EN
Published: Nature Portfolio 2020
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Online Access:https://doaj.org/article/89f05c7d9acb4c02bc6f16d5f62bae88
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Summary:Alkyl carboxylic acids and primary amines are ubiquitous and useful for synthesis of new compounds. Here, the authors report a manganese-mediated reductive decarboxylative/deaminative functionalization of activated aliphatic acids and primary amines for construction of C-C and C-X bonds under mild conditions.