Rule knowledge aids performance on spatial and object alternation tasks by alcoholic patients with and without Korsakoff’s amnesia

Rule knowledge aids performance on spatial and object alternation tasks by alcoholic patients with and without Korsakoff’s amnesia

Fiona J Bardenhagen1,2, Marlene Oscar-Berman3, Stephen C Bowden2,41School of Psychology, Victoria University, Melbourne, Victoria, Australia; 2Clinical Neurosciences, St. Vincent’s Hospital, Melbourne, Australia; 3Division of Psychiatry and Departments of Neurology and Anatomy and Neur...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Fiona J Bardenhagen, Marlene Oscar-Berman, Stephen C Bowden
Formato: article
Lenguaje:EN
Publicado: Dove Medical Press 2007
Materias:
Neurosciences. Biological psychiatry. Neuropsychiatry
RC321-571
Neurology. Diseases of the nervous system
RC346-429
Acceso en línea:https://doaj.org/article/89f5d50704f04310b6d9baef2583ab37
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:89f5d50704f04310b6d9baef2583ab37
record_format dspace
spelling oai:doaj.org-article:89f5d50704f04310b6d9baef2583ab372021-12-02T06:22:20ZRule knowledge aids performance on spatial and object alternation tasks by alcoholic patients with and without Korsakoff’s amnesia1176-63281178-2021https://doaj.org/article/89f5d50704f04310b6d9baef2583ab372007-01-01T00:00:00Zhttp://www.dovepress.com/rule-knowledge-aids-performance-on-spatial-and-object-alternation-task-a970https://doaj.org/toc/1176-6328https://doaj.org/toc/1178-2021Fiona J Bardenhagen1,2, Marlene Oscar-Berman3, Stephen C Bowden2,41School of Psychology, Victoria University, Melbourne, Victoria, Australia; 2Clinical Neurosciences, St. Vincent’s Hospital, Melbourne, Australia; 3Division of Psychiatry and Departments of Neurology and Anatomy and Neurobiology, Boston University School of Medicine; and Psychology Research Service, US Department of Veterans Affairs (VA) Healthcare System, Jamaica Plain Campus, MA, USA; 4School of Behavioural Science, University of Melbourne, Parkville, Victoria, AustraliaAbstract: Delayed alternation (DA) and object alternation (OA) tasks traditionally have been used to measure defective response inhibition associated with dysfunction of frontal brain systems. However, these tasks are also sensitive to nonfrontal lesions, and cognitive processes such as the induction of rule-learning strategies also are needed in order to perform well on these tasks. Performance on DA and OA tasks was explored in 10 patients with alcohol-induced persisting amnestic disorder (Korsakoff’s syndrome), 11 abstinent long-term alcoholics, and 13 healthy non-alcoholic controls under each of two rule provision conditions: Alternation Rule and Correction Rule. Results confirmed that rule knowledge is a crucial cognitive component for solving problems such as DA and OA, and therefore, that errors on these tasks are not due to defective response inhibition alone. Further, rule-induction strategies were helpful to Korsakoff patients, despite their poorer performance on the tasks. These results stress the role of multiple cognitive abilities in successful performance on rule induction tasks. Evidence that these cognitive abilities are served by diffusely distributed neural networks should be considered when interpreting behavioral impairments on these tasks.Keywords: alcoholism, Korsakoff’s syndrome, comparative neuropsychology, perseveration, rule induction, working memory Fiona J BardenhagenMarlene Oscar-BermanStephen C BowdenDove Medical PressarticleNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol 2007, Iss Issue 6, Pp 907-918 (2007)
institution DOAJ
collection DOAJ
language EN
topic Neurosciences. Biological psychiatry. Neuropsychiatry
RC321-571
Neurology. Diseases of the nervous system
RC346-429
spellingShingle Neurosciences. Biological psychiatry. Neuropsychiatry
RC321-571
Neurology. Diseases of the nervous system
RC346-429
Fiona J Bardenhagen
Marlene Oscar-Berman
Stephen C Bowden
Rule knowledge aids performance on spatial and object alternation tasks by alcoholic patients with and without Korsakoff’s amnesia
description Fiona J Bardenhagen1,2, Marlene Oscar-Berman3, Stephen C Bowden2,41School of Psychology, Victoria University, Melbourne, Victoria, Australia; 2Clinical Neurosciences, St. Vincent’s Hospital, Melbourne, Australia; 3Division of Psychiatry and Departments of Neurology and Anatomy and Neurobiology, Boston University School of Medicine; and Psychology Research Service, US Department of Veterans Affairs (VA) Healthcare System, Jamaica Plain Campus, MA, USA; 4School of Behavioural Science, University of Melbourne, Parkville, Victoria, AustraliaAbstract: Delayed alternation (DA) and object alternation (OA) tasks traditionally have been used to measure defective response inhibition associated with dysfunction of frontal brain systems. However, these tasks are also sensitive to nonfrontal lesions, and cognitive processes such as the induction of rule-learning strategies also are needed in order to perform well on these tasks. Performance on DA and OA tasks was explored in 10 patients with alcohol-induced persisting amnestic disorder (Korsakoff’s syndrome), 11 abstinent long-term alcoholics, and 13 healthy non-alcoholic controls under each of two rule provision conditions: Alternation Rule and Correction Rule. Results confirmed that rule knowledge is a crucial cognitive component for solving problems such as DA and OA, and therefore, that errors on these tasks are not due to defective response inhibition alone. Further, rule-induction strategies were helpful to Korsakoff patients, despite their poorer performance on the tasks. These results stress the role of multiple cognitive abilities in successful performance on rule induction tasks. Evidence that these cognitive abilities are served by diffusely distributed neural networks should be considered when interpreting behavioral impairments on these tasks.Keywords: alcoholism, Korsakoff’s syndrome, comparative neuropsychology, perseveration, rule induction, working memory
format article
author Fiona J Bardenhagen
Marlene Oscar-Berman
Stephen C Bowden
author_facet Fiona J Bardenhagen
Marlene Oscar-Berman
Stephen C Bowden
author_sort Fiona J Bardenhagen
title Rule knowledge aids performance on spatial and object alternation tasks by alcoholic patients with and without Korsakoff’s amnesia
title_short Rule knowledge aids performance on spatial and object alternation tasks by alcoholic patients with and without Korsakoff’s amnesia
title_full Rule knowledge aids performance on spatial and object alternation tasks by alcoholic patients with and without Korsakoff’s amnesia
title_fullStr Rule knowledge aids performance on spatial and object alternation tasks by alcoholic patients with and without Korsakoff’s amnesia
title_full_unstemmed Rule knowledge aids performance on spatial and object alternation tasks by alcoholic patients with and without Korsakoff’s amnesia
title_sort rule knowledge aids performance on spatial and object alternation tasks by alcoholic patients with and without korsakoff’s amnesia
publisher Dove Medical Press
publishDate 2007
url https://doaj.org/article/89f5d50704f04310b6d9baef2583ab37
work_keys_str_mv AT fionajbardenhagen ruleknowledgeaidsperformanceonspatialandobjectalternationtasksbyalcoholicpatientswithandwithoutkorsakoffamprsquosamnesia
AT marleneoscarberman ruleknowledgeaidsperformanceonspatialandobjectalternationtasksbyalcoholicpatientswithandwithoutkorsakoffamprsquosamnesia
AT stephencbowden ruleknowledgeaidsperformanceonspatialandobjectalternationtasksbyalcoholicpatientswithandwithoutkorsakoffamprsquosamnesia
_version_ 1718399946317627392

Ejemplares similares