Collective cell mechanics of epithelial shells with organoid-like morphologies

The physical origins of man-made tissue morphologies with organ-like microscopic anatomy and functionality remain poorly understood. Here, authors propose a mechanistic theory of these structures, employing a 3D vertex model to reproduce the characteristic morphologies such as branched shapes.

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Detalles Bibliográficos
Autores principales:	Jan Rozman, Matej Krajnc, Primož Ziherl
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/89f72efd68ce42ac98995d4580317551
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spelling	oai:doaj.org-article:89f72efd68ce42ac98995d45803175512021-12-02T16:24:54ZCollective cell mechanics of epithelial shells with organoid-like morphologies10.1038/s41467-020-17535-42041-1723https://doaj.org/article/89f72efd68ce42ac98995d45803175512020-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17535-4https://doaj.org/toc/2041-1723The physical origins of man-made tissue morphologies with organ-like microscopic anatomy and functionality remain poorly understood. Here, authors propose a mechanistic theory of these structures, employing a 3D vertex model to reproduce the characteristic morphologies such as branched shapes.Jan RozmanMatej KrajncPrimož ZiherlNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jan Rozman Matej Krajnc Primož Ziherl Collective cell mechanics of epithelial shells with organoid-like morphologies
description	The physical origins of man-made tissue morphologies with organ-like microscopic anatomy and functionality remain poorly understood. Here, authors propose a mechanistic theory of these structures, employing a 3D vertex model to reproduce the characteristic morphologies such as branched shapes.
format	article
author	Jan Rozman Matej Krajnc Primož Ziherl
author_facet	Jan Rozman Matej Krajnc Primož Ziherl
author_sort	Jan Rozman
title	Collective cell mechanics of epithelial shells with organoid-like morphologies
title_short	Collective cell mechanics of epithelial shells with organoid-like morphologies
title_full	Collective cell mechanics of epithelial shells with organoid-like morphologies
title_fullStr	Collective cell mechanics of epithelial shells with organoid-like morphologies
title_full_unstemmed	Collective cell mechanics of epithelial shells with organoid-like morphologies
title_sort	collective cell mechanics of epithelial shells with organoid-like morphologies
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/89f72efd68ce42ac98995d4580317551
work_keys_str_mv	AT janrozman collectivecellmechanicsofepithelialshellswithorganoidlikemorphologies AT matejkrajnc collectivecellmechanicsofepithelialshellswithorganoidlikemorphologies AT primozziherl collectivecellmechanicsofepithelialshellswithorganoidlikemorphologies
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Collective cell mechanics of epithelial shells with organoid-like morphologies

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