Cytosine modifications exhibit circadian oscillations that are involved in epigenetic diversity and aging

While epigenetic factors have been implicated in the circadian rhythm, the detection of circadian cytosine modifications has remained elusive. Here the authors identify a large number of epigenetically variable cytosines that show circadian oscillations in their modification status in mice.

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Autores principales: Gabriel Oh, Sasha Ebrahimi, Matthew Carlucci, Aiping Zhang, Akhil Nair, Daniel E. Groot, Viviane Labrie, Peixin Jia, Edward S. Oh, Richie H. Jeremian, Miki Susic, Tenjin C. Shrestha, Martin R. Ralph, Juozas Gordevičius, Karolis Koncevičius, Art Petronis
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/89f9083153cf4657915ee2a746f9e965
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spelling oai:doaj.org-article:89f9083153cf4657915ee2a746f9e9652021-12-02T15:33:42ZCytosine modifications exhibit circadian oscillations that are involved in epigenetic diversity and aging10.1038/s41467-018-03073-72041-1723https://doaj.org/article/89f9083153cf4657915ee2a746f9e9652018-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03073-7https://doaj.org/toc/2041-1723While epigenetic factors have been implicated in the circadian rhythm, the detection of circadian cytosine modifications has remained elusive. Here the authors identify a large number of epigenetically variable cytosines that show circadian oscillations in their modification status in mice.Gabriel OhSasha EbrahimiMatthew CarlucciAiping ZhangAkhil NairDaniel E. GrootViviane LabriePeixin JiaEdward S. OhRichie H. JeremianMiki SusicTenjin C. ShresthaMartin R. RalphJuozas GordevičiusKarolis KoncevičiusArt PetronisNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Gabriel Oh
Sasha Ebrahimi
Matthew Carlucci
Aiping Zhang
Akhil Nair
Daniel E. Groot
Viviane Labrie
Peixin Jia
Edward S. Oh
Richie H. Jeremian
Miki Susic
Tenjin C. Shrestha
Martin R. Ralph
Juozas Gordevičius
Karolis Koncevičius
Art Petronis
Cytosine modifications exhibit circadian oscillations that are involved in epigenetic diversity and aging
description While epigenetic factors have been implicated in the circadian rhythm, the detection of circadian cytosine modifications has remained elusive. Here the authors identify a large number of epigenetically variable cytosines that show circadian oscillations in their modification status in mice.
format article
author Gabriel Oh
Sasha Ebrahimi
Matthew Carlucci
Aiping Zhang
Akhil Nair
Daniel E. Groot
Viviane Labrie
Peixin Jia
Edward S. Oh
Richie H. Jeremian
Miki Susic
Tenjin C. Shrestha
Martin R. Ralph
Juozas Gordevičius
Karolis Koncevičius
Art Petronis
author_facet Gabriel Oh
Sasha Ebrahimi
Matthew Carlucci
Aiping Zhang
Akhil Nair
Daniel E. Groot
Viviane Labrie
Peixin Jia
Edward S. Oh
Richie H. Jeremian
Miki Susic
Tenjin C. Shrestha
Martin R. Ralph
Juozas Gordevičius
Karolis Koncevičius
Art Petronis
author_sort Gabriel Oh
title Cytosine modifications exhibit circadian oscillations that are involved in epigenetic diversity and aging
title_short Cytosine modifications exhibit circadian oscillations that are involved in epigenetic diversity and aging
title_full Cytosine modifications exhibit circadian oscillations that are involved in epigenetic diversity and aging
title_fullStr Cytosine modifications exhibit circadian oscillations that are involved in epigenetic diversity and aging
title_full_unstemmed Cytosine modifications exhibit circadian oscillations that are involved in epigenetic diversity and aging
title_sort cytosine modifications exhibit circadian oscillations that are involved in epigenetic diversity and aging
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/89f9083153cf4657915ee2a746f9e965
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