Cytosine modifications exhibit circadian oscillations that are involved in epigenetic diversity and aging
While epigenetic factors have been implicated in the circadian rhythm, the detection of circadian cytosine modifications has remained elusive. Here the authors identify a large number of epigenetically variable cytosines that show circadian oscillations in their modification status in mice.
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Nature Portfolio
2018
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oai:doaj.org-article:89f9083153cf4657915ee2a746f9e9652021-12-02T15:33:42ZCytosine modifications exhibit circadian oscillations that are involved in epigenetic diversity and aging10.1038/s41467-018-03073-72041-1723https://doaj.org/article/89f9083153cf4657915ee2a746f9e9652018-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03073-7https://doaj.org/toc/2041-1723While epigenetic factors have been implicated in the circadian rhythm, the detection of circadian cytosine modifications has remained elusive. Here the authors identify a large number of epigenetically variable cytosines that show circadian oscillations in their modification status in mice.Gabriel OhSasha EbrahimiMatthew CarlucciAiping ZhangAkhil NairDaniel E. GrootViviane LabriePeixin JiaEdward S. OhRichie H. JeremianMiki SusicTenjin C. ShresthaMartin R. RalphJuozas GordevičiusKarolis KoncevičiusArt PetronisNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018) |
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Science Q |
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Science Q Gabriel Oh Sasha Ebrahimi Matthew Carlucci Aiping Zhang Akhil Nair Daniel E. Groot Viviane Labrie Peixin Jia Edward S. Oh Richie H. Jeremian Miki Susic Tenjin C. Shrestha Martin R. Ralph Juozas Gordevičius Karolis Koncevičius Art Petronis Cytosine modifications exhibit circadian oscillations that are involved in epigenetic diversity and aging |
description |
While epigenetic factors have been implicated in the circadian rhythm, the detection of circadian cytosine modifications has remained elusive. Here the authors identify a large number of epigenetically variable cytosines that show circadian oscillations in their modification status in mice. |
format |
article |
author |
Gabriel Oh Sasha Ebrahimi Matthew Carlucci Aiping Zhang Akhil Nair Daniel E. Groot Viviane Labrie Peixin Jia Edward S. Oh Richie H. Jeremian Miki Susic Tenjin C. Shrestha Martin R. Ralph Juozas Gordevičius Karolis Koncevičius Art Petronis |
author_facet |
Gabriel Oh Sasha Ebrahimi Matthew Carlucci Aiping Zhang Akhil Nair Daniel E. Groot Viviane Labrie Peixin Jia Edward S. Oh Richie H. Jeremian Miki Susic Tenjin C. Shrestha Martin R. Ralph Juozas Gordevičius Karolis Koncevičius Art Petronis |
author_sort |
Gabriel Oh |
title |
Cytosine modifications exhibit circadian oscillations that are involved in epigenetic diversity and aging |
title_short |
Cytosine modifications exhibit circadian oscillations that are involved in epigenetic diversity and aging |
title_full |
Cytosine modifications exhibit circadian oscillations that are involved in epigenetic diversity and aging |
title_fullStr |
Cytosine modifications exhibit circadian oscillations that are involved in epigenetic diversity and aging |
title_full_unstemmed |
Cytosine modifications exhibit circadian oscillations that are involved in epigenetic diversity and aging |
title_sort |
cytosine modifications exhibit circadian oscillations that are involved in epigenetic diversity and aging |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/89f9083153cf4657915ee2a746f9e965 |
work_keys_str_mv |
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