Telomere damage promotes vascular smooth muscle cell senescence and immune cell recruitment after vessel injury

Telomere damage promotes vascular smooth muscle cell senescence and immune cell recruitment after vessel injury

Anna Uryga and Mandy Grootaert et al. combine cell culture and animal models to examine how senescence of human vascular smooth muscle cells (VSMCs) and persistent telomere damage drive inflammation. Their results suggest that telomere injury can be the primary cause of premature senescence in VSMCs...

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Bibliographic Details
Main Authors: Anna K. Uryga, Mandy O. J. Grootaert, Abel M. Garrido, Sebnem Oc, Kirsty Foote, Joel Chappell, Alison Finigan, Francesca Rossiello, Fabrizio d’Adda di Fagagna, Dimitra Aravani, Helle F. Jorgensen, Martin R. Bennett
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Biology (General)
QH301-705.5
Online Access:https://doaj.org/article/89fb7bb2970a4e30ac925d9236fd3bc3
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https://doaj.org/article/89fb7bb2970a4e30ac925d9236fd3bc3

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