Mutations as Levy flights

Abstract Data from a long time evolution experiment with Escherichia Coli and from a large study on copy number variations in subjects with European ancestry are analyzed in order to argue that mutations can be described as Levy flights in the mutation space. These Levy flights have at least two com...

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Autores principales:	Dario A. Leon, Augusto Gonzalez
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/8a0bb5ed6bee48dd81b75449ca296d62
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spelling	oai:doaj.org-article:8a0bb5ed6bee48dd81b75449ca296d622021-12-02T15:36:13ZMutations as Levy flights10.1038/s41598-021-88012-12045-2322https://doaj.org/article/8a0bb5ed6bee48dd81b75449ca296d622021-05-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-88012-1https://doaj.org/toc/2045-2322Abstract Data from a long time evolution experiment with Escherichia Coli and from a large study on copy number variations in subjects with European ancestry are analyzed in order to argue that mutations can be described as Levy flights in the mutation space. These Levy flights have at least two components: random single-base substitutions and large DNA rearrangements. From the data, we get estimations for the time rates of both events and the size distribution function of large rearrangements.Dario A. LeonAugusto GonzalezNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Dario A. Leon Augusto Gonzalez Mutations as Levy flights
description	Abstract Data from a long time evolution experiment with Escherichia Coli and from a large study on copy number variations in subjects with European ancestry are analyzed in order to argue that mutations can be described as Levy flights in the mutation space. These Levy flights have at least two components: random single-base substitutions and large DNA rearrangements. From the data, we get estimations for the time rates of both events and the size distribution function of large rearrangements.
format	article
author	Dario A. Leon Augusto Gonzalez
author_facet	Dario A. Leon Augusto Gonzalez
author_sort	Dario A. Leon
title	Mutations as Levy flights
title_short	Mutations as Levy flights
title_full	Mutations as Levy flights
title_fullStr	Mutations as Levy flights
title_full_unstemmed	Mutations as Levy flights
title_sort	mutations as levy flights
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/8a0bb5ed6bee48dd81b75449ca296d62
work_keys_str_mv	AT darioaleon mutationsaslevyflights AT augustogonzalez mutationsaslevyflights
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Mutations as Levy flights

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