Structural and mechanistic insights into regulation of the retromer coat by TBC1d5

Retromer is recruited to endosomes by the small GTPase Rab7 and sorting nexin 3. Here, the authors report the interaction between a GTPase-activating protein TBC1d5 and Rab7, examine the biochemical details of the interaction with retromer, and discuss the implications for receptor trafficking.

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Autores principales:	Da Jia, Jin-San Zhang, Fang Li, Jing Wang, Zhihui Deng, Mark A. White, Douglas G. Osborne, Christine Phillips-Krawczak, Timothy S. Gomez, Haiying Li, Amika Singla, Ezra Burstein, Daniel D. Billadeau, Michael K. Rosen
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/8a2c8da8d4ec4c028e1d80ce552e2374
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spelling	oai:doaj.org-article:8a2c8da8d4ec4c028e1d80ce552e23742021-12-02T16:49:40ZStructural and mechanistic insights into regulation of the retromer coat by TBC1d510.1038/ncomms133052041-1723https://doaj.org/article/8a2c8da8d4ec4c028e1d80ce552e23742016-11-01T00:00:00Zhttps://doi.org/10.1038/ncomms13305https://doaj.org/toc/2041-1723Retromer is recruited to endosomes by the small GTPase Rab7 and sorting nexin 3. Here, the authors report the interaction between a GTPase-activating protein TBC1d5 and Rab7, examine the biochemical details of the interaction with retromer, and discuss the implications for receptor trafficking.Da JiaJin-San ZhangFang LiJing WangZhihui DengMark A. WhiteDouglas G. OsborneChristine Phillips-KrawczakTimothy S. GomezHaiying LiAmika SinglaEzra BursteinDaniel D. BilladeauMichael K. RosenNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Da Jia Jin-San Zhang Fang Li Jing Wang Zhihui Deng Mark A. White Douglas G. Osborne Christine Phillips-Krawczak Timothy S. Gomez Haiying Li Amika Singla Ezra Burstein Daniel D. Billadeau Michael K. Rosen Structural and mechanistic insights into regulation of the retromer coat by TBC1d5
description	Retromer is recruited to endosomes by the small GTPase Rab7 and sorting nexin 3. Here, the authors report the interaction between a GTPase-activating protein TBC1d5 and Rab7, examine the biochemical details of the interaction with retromer, and discuss the implications for receptor trafficking.
format	article
author	Da Jia Jin-San Zhang Fang Li Jing Wang Zhihui Deng Mark A. White Douglas G. Osborne Christine Phillips-Krawczak Timothy S. Gomez Haiying Li Amika Singla Ezra Burstein Daniel D. Billadeau Michael K. Rosen
author_facet	Da Jia Jin-San Zhang Fang Li Jing Wang Zhihui Deng Mark A. White Douglas G. Osborne Christine Phillips-Krawczak Timothy S. Gomez Haiying Li Amika Singla Ezra Burstein Daniel D. Billadeau Michael K. Rosen
author_sort	Da Jia
title	Structural and mechanistic insights into regulation of the retromer coat by TBC1d5
title_short	Structural and mechanistic insights into regulation of the retromer coat by TBC1d5
title_full	Structural and mechanistic insights into regulation of the retromer coat by TBC1d5
title_fullStr	Structural and mechanistic insights into regulation of the retromer coat by TBC1d5
title_full_unstemmed	Structural and mechanistic insights into regulation of the retromer coat by TBC1d5
title_sort	structural and mechanistic insights into regulation of the retromer coat by tbc1d5
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/8a2c8da8d4ec4c028e1d80ce552e2374
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Structural and mechanistic insights into regulation of the retromer coat by TBC1d5

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