Microglia have a grip on brain microvasculature

Microglia are brain resident immune cells with multiple functions. However, little is known about microglia-vascular interactions. In a recent paper published in Nature Communications, Bisht et al. identify a signalling mechanism that attracts and maintains microglia at the capillary wall. Moreover,...

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Autores principales: Kassandra Kisler, Angeliki Maria Nikolakopoulou, Berislav V. Zlokovic
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/8a33430feb074dc1b7cc19559bb0766d
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spelling oai:doaj.org-article:8a33430feb074dc1b7cc19559bb0766d2021-12-02T14:55:15ZMicroglia have a grip on brain microvasculature10.1038/s41467-021-25595-32041-1723https://doaj.org/article/8a33430feb074dc1b7cc19559bb0766d2021-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25595-3https://doaj.org/toc/2041-1723Microglia are brain resident immune cells with multiple functions. However, little is known about microglia-vascular interactions. In a recent paper published in Nature Communications, Bisht et al. identify a signalling mechanism that attracts and maintains microglia at the capillary wall. Moreover, they show that microglia regulate capillary vascular tone, playing a more significant role in blood flow regulation than previously thought.Kassandra KislerAngeliki Maria NikolakopoulouBerislav V. ZlokovicNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-3 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Kassandra Kisler
Angeliki Maria Nikolakopoulou
Berislav V. Zlokovic
Microglia have a grip on brain microvasculature
description Microglia are brain resident immune cells with multiple functions. However, little is known about microglia-vascular interactions. In a recent paper published in Nature Communications, Bisht et al. identify a signalling mechanism that attracts and maintains microglia at the capillary wall. Moreover, they show that microglia regulate capillary vascular tone, playing a more significant role in blood flow regulation than previously thought.
format article
author Kassandra Kisler
Angeliki Maria Nikolakopoulou
Berislav V. Zlokovic
author_facet Kassandra Kisler
Angeliki Maria Nikolakopoulou
Berislav V. Zlokovic
author_sort Kassandra Kisler
title Microglia have a grip on brain microvasculature
title_short Microglia have a grip on brain microvasculature
title_full Microglia have a grip on brain microvasculature
title_fullStr Microglia have a grip on brain microvasculature
title_full_unstemmed Microglia have a grip on brain microvasculature
title_sort microglia have a grip on brain microvasculature
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/8a33430feb074dc1b7cc19559bb0766d
work_keys_str_mv AT kassandrakisler microgliahaveagriponbrainmicrovasculature
AT angelikimarianikolakopoulou microgliahaveagriponbrainmicrovasculature
AT berislavvzlokovic microgliahaveagriponbrainmicrovasculature
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