Cellular senescence promotes endothelial activation through epigenetic alteration, and consequently accelerates atherosclerosis
Abstract Senescent vascular cells are detected in atherosclerotic lesion, and its involvement in the development of atherosclerosis has been revealed; however, whether and the mechanism by which endothelial cell (EC) senescence is causally implicated in atherosclerosis remains unclear. We here inves...
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Autores principales: | Sakiko Honda, Koji Ikeda, Ryota Urata, Ekura Yamazaki, Noriaki Emoto, Satoaki Matoba |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/8a34ecd3f6314f959460d8035c051b9c |
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