Gene regulatory network analysis defines transcriptome landscape with alternative splicing of human umbilical vein endothelial cells during replicative senescence
Abstract Background Endothelial cell senescence is the state of permanent cell cycle arrest and plays a critical role in the pathogenesis of age-related diseases. However, a comprehensive understanding of the gene regulatory network, including genome-wide alternative splicing machinery, involved in...
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Autores principales: | , , , , , , |
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Formato: | article |
Lenguaje: | EN |
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BMC
2021
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Acceso en línea: | https://doaj.org/article/8a3ccdb38a2246d8b51530ba78db631f |
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