Palladium nanoparticles entrapped in a self-supporting nanoporous gold wire as sensitive dopamine biosensor

Abstract Traced dopamine (DA) detection is critical for the early diagnosis and prevention of some diseases such as Parkinson’s, Alzheimer and schizophrenia. In this research, a novel self-supporting three dimensional (3D) bicontinuous nanoporous electrochemical biosensor was developed for the detec...

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Autores principales:	Xin Yi, Yuxuan Wu, Guoxin Tan, Peng Yu, Lei Zhou, Zhengnan Zhou, Junqi Chen, Zhengao Wang, Jinshan Pang, Chengyun Ning
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/8a4892213a214dcfa559266dc54e8ecf
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spelling	oai:doaj.org-article:8a4892213a214dcfa559266dc54e8ecf2021-12-02T12:30:11ZPalladium nanoparticles entrapped in a self-supporting nanoporous gold wire as sensitive dopamine biosensor10.1038/s41598-017-07909-y2045-2322https://doaj.org/article/8a4892213a214dcfa559266dc54e8ecf2017-08-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-07909-yhttps://doaj.org/toc/2045-2322Abstract Traced dopamine (DA) detection is critical for the early diagnosis and prevention of some diseases such as Parkinson’s, Alzheimer and schizophrenia. In this research, a novel self-supporting three dimensional (3D) bicontinuous nanoporous electrochemical biosensor was developed for the detection of dopamine by Differential Pulse Voltammetry (DPV). This biosensor was fabricated by electrodepositing palladium nanoparticles (Pd) onto self-supporting nanoporous gold (NPG) wire. Because of the synergistic effects of the excellent catalytic activity of Pd and novel structure of NPG wire, the palladium nanoparticles decorated NPG (Pd/NPG) biosensor possess tremendous superiority in the detection of DA. The Pd/NPG wire biosensor exhibited high sensitivity of 1.19 μA μΜ−1, broad detection range of 1–220 μM and low detection limit up to 1 μM. Besides, the proposed dopamine biosensor possessed good stability, reproducibility, reusability and selectivity. The response currents of detection in the fetal bovine serum were also close to the standard solutions. Therefore the Pd/NPG wire biosensor is promising to been used in clinic.Xin YiYuxuan WuGuoxin TanPeng YuLei ZhouZhengnan ZhouJunqi ChenZhengao WangJinshan PangChengyun NingNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Xin Yi Yuxuan Wu Guoxin Tan Peng Yu Lei Zhou Zhengnan Zhou Junqi Chen Zhengao Wang Jinshan Pang Chengyun Ning Palladium nanoparticles entrapped in a self-supporting nanoporous gold wire as sensitive dopamine biosensor
description	Abstract Traced dopamine (DA) detection is critical for the early diagnosis and prevention of some diseases such as Parkinson’s, Alzheimer and schizophrenia. In this research, a novel self-supporting three dimensional (3D) bicontinuous nanoporous electrochemical biosensor was developed for the detection of dopamine by Differential Pulse Voltammetry (DPV). This biosensor was fabricated by electrodepositing palladium nanoparticles (Pd) onto self-supporting nanoporous gold (NPG) wire. Because of the synergistic effects of the excellent catalytic activity of Pd and novel structure of NPG wire, the palladium nanoparticles decorated NPG (Pd/NPG) biosensor possess tremendous superiority in the detection of DA. The Pd/NPG wire biosensor exhibited high sensitivity of 1.19 μA μΜ−1, broad detection range of 1–220 μM and low detection limit up to 1 μM. Besides, the proposed dopamine biosensor possessed good stability, reproducibility, reusability and selectivity. The response currents of detection in the fetal bovine serum were also close to the standard solutions. Therefore the Pd/NPG wire biosensor is promising to been used in clinic.
format	article
author	Xin Yi Yuxuan Wu Guoxin Tan Peng Yu Lei Zhou Zhengnan Zhou Junqi Chen Zhengao Wang Jinshan Pang Chengyun Ning
author_facet	Xin Yi Yuxuan Wu Guoxin Tan Peng Yu Lei Zhou Zhengnan Zhou Junqi Chen Zhengao Wang Jinshan Pang Chengyun Ning
author_sort	Xin Yi
title	Palladium nanoparticles entrapped in a self-supporting nanoporous gold wire as sensitive dopamine biosensor
title_short	Palladium nanoparticles entrapped in a self-supporting nanoporous gold wire as sensitive dopamine biosensor
title_full	Palladium nanoparticles entrapped in a self-supporting nanoporous gold wire as sensitive dopamine biosensor
title_fullStr	Palladium nanoparticles entrapped in a self-supporting nanoporous gold wire as sensitive dopamine biosensor
title_full_unstemmed	Palladium nanoparticles entrapped in a self-supporting nanoporous gold wire as sensitive dopamine biosensor
title_sort	palladium nanoparticles entrapped in a self-supporting nanoporous gold wire as sensitive dopamine biosensor
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/8a4892213a214dcfa559266dc54e8ecf
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Palladium nanoparticles entrapped in a self-supporting nanoporous gold wire as sensitive dopamine biosensor

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