The atypical chemokine receptor ACKR3/CXCR7 is a broad-spectrum scavenger for opioid peptides

Opioids modulate pain, anxiety and stress by activating four subtypes of opioid receptors. The authors show that atypical chemokine receptor 3 (ACKR3) is a scavenger for various endogenous opioid peptides regulating their availability without activating downstream signaling.

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Autores principales:	Max Meyrath, Martyna Szpakowska, Julian Zeiner, Laurent Massotte, Myriam P. Merz, Tobias Benkel, Katharina Simon, Jochen Ohnmacht, Jonathan D. Turner, Rejko Krüger, Vincent Seutin, Markus Ollert, Evi Kostenis, Andy Chevigné
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/8a4a6653d741478ead90254a5b4ed525
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spelling	oai:doaj.org-article:8a4a6653d741478ead90254a5b4ed5252021-12-02T16:04:34ZThe atypical chemokine receptor ACKR3/CXCR7 is a broad-spectrum scavenger for opioid peptides10.1038/s41467-020-16664-02041-1723https://doaj.org/article/8a4a6653d741478ead90254a5b4ed5252020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16664-0https://doaj.org/toc/2041-1723Opioids modulate pain, anxiety and stress by activating four subtypes of opioid receptors. The authors show that atypical chemokine receptor 3 (ACKR3) is a scavenger for various endogenous opioid peptides regulating their availability without activating downstream signaling.Max MeyrathMartyna SzpakowskaJulian ZeinerLaurent MassotteMyriam P. MerzTobias BenkelKatharina SimonJochen OhnmachtJonathan D. TurnerRejko KrügerVincent SeutinMarkus OllertEvi KostenisAndy ChevignéNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Max Meyrath Martyna Szpakowska Julian Zeiner Laurent Massotte Myriam P. Merz Tobias Benkel Katharina Simon Jochen Ohnmacht Jonathan D. Turner Rejko Krüger Vincent Seutin Markus Ollert Evi Kostenis Andy Chevigné The atypical chemokine receptor ACKR3/CXCR7 is a broad-spectrum scavenger for opioid peptides
description	Opioids modulate pain, anxiety and stress by activating four subtypes of opioid receptors. The authors show that atypical chemokine receptor 3 (ACKR3) is a scavenger for various endogenous opioid peptides regulating their availability without activating downstream signaling.
format	article
author	Max Meyrath Martyna Szpakowska Julian Zeiner Laurent Massotte Myriam P. Merz Tobias Benkel Katharina Simon Jochen Ohnmacht Jonathan D. Turner Rejko Krüger Vincent Seutin Markus Ollert Evi Kostenis Andy Chevigné
author_facet	Max Meyrath Martyna Szpakowska Julian Zeiner Laurent Massotte Myriam P. Merz Tobias Benkel Katharina Simon Jochen Ohnmacht Jonathan D. Turner Rejko Krüger Vincent Seutin Markus Ollert Evi Kostenis Andy Chevigné
author_sort	Max Meyrath
title	The atypical chemokine receptor ACKR3/CXCR7 is a broad-spectrum scavenger for opioid peptides
title_short	The atypical chemokine receptor ACKR3/CXCR7 is a broad-spectrum scavenger for opioid peptides
title_full	The atypical chemokine receptor ACKR3/CXCR7 is a broad-spectrum scavenger for opioid peptides
title_fullStr	The atypical chemokine receptor ACKR3/CXCR7 is a broad-spectrum scavenger for opioid peptides
title_full_unstemmed	The atypical chemokine receptor ACKR3/CXCR7 is a broad-spectrum scavenger for opioid peptides
title_sort	atypical chemokine receptor ackr3/cxcr7 is a broad-spectrum scavenger for opioid peptides
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/8a4a6653d741478ead90254a5b4ed525
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The atypical chemokine receptor ACKR3/CXCR7 is a broad-spectrum scavenger for opioid peptides

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